STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (360 aa)    
Predicted Functional Partners:
aroA
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
 
 
 0.995
SLJ87354.1
Chorismate mutase.
  
 
 0.984
aroE
Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
 
 0.978
aroB
3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
 
 
 0.974
SLJ89030.1
Anthranilate synthase, component I.
 
 
 0.973
SLJ89048.1
Anthranilate synthase component 2.
 
 
 0.967
SLJ90874.1
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
   
   0.959
SLK07430.1
Cyclohexadieny/prephenate dehydrogenase.
  
 0.949
SLJ98970.1
Para-aminobenzoate synthetase component 1.
 
 
 0.940
SLJ94494.1
Para-aminobenzoate synthetase / 4-amino-4-deoxychorismate lyase.
 
 
 0.921
Your Current Organism:
Novosphingobium mathurense
NCBI taxonomy Id: 428990
Other names: CCM 7473, MTCC 9020, N. mathurense, Novosphingobium mathurense Gupta et al. 2009, Novosphingobium sp. SM117, strain SM117
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