STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
edd6-phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. (604 aa)    
Predicted Functional Partners:
SLK05059.1
2-keto-3-deoxy-phosphogluconate aldolase.
 
 
 0.998
SLK05593.1
6-phosphogluconolactonase.
 
 
 0.994
zwf
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
 
 
 0.993
glk
Glucokinase; Belongs to the bacterial glucokinase family.
 
 
 0.980
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
 
 
 0.927
SLJ93777.1
Glutamate synthase (NADH) large subunit.
  
  
 0.880
leuC
3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
 
 
 0.858
SLJ87026.1
Branched chain amino acid aminotransferase apoenzyme.
  
 0.855
SLJ99064.1
2-dehydro-3-deoxygluconokinase.
    
 0.842
SLJ94494.1
Para-aminobenzoate synthetase / 4-amino-4-deoxychorismate lyase.
  
 0.821
Your Current Organism:
Novosphingobium mathurense
NCBI taxonomy Id: 428990
Other names: CCM 7473, MTCC 9020, N. mathurense, Novosphingobium mathurense Gupta et al. 2009, Novosphingobium sp. SM117, strain SM117
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