STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDH36880.1Alkylated DNA repair dioxygenase AlkB. (199 aa)    
Predicted Functional Partners:
SDH36905.1
Hypothetical protein.
       0.803
SDH78561.1
2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
   
    0.776
SDI43800.1
2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
   
    0.776
SDH36855.1
Hypothetical protein.
       0.658
SDH44332.1
5'-methylthioinosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine.
 
      0.600
SDH67425.1
AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase.
  
  
 0.578
SDI17343.1
4-hydroxyphenylpyruvate dioxygenase.
  
    0.568
SDH77826.1
DNA-3-methyladenine glycosylase II.
  
  
 0.535
SDH36927.1
Hypothetical protein.
       0.503
SDH77807.1
methylated-DNA-[protein]-cysteine S-methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
 
  
 0.456
Your Current Organism:
Pseudomonas panipatensis
NCBI taxonomy Id: 428992
Other names: CCM 7469, MTCC 8990, P. panipatensis, Pseudomonas panipatensis Gupta et al. 2008, Pseudomonas sp. Esp-1, strain Esp-1
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