node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDH80349.1 | SDI34808.1 | SAMN05216272_103189 | SAMN05216272_10872 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Hypothetical protein. | 0.784 |
SDH80349.1 | SDI67863.1 | SAMN05216272_103189 | SAMN05216272_11574 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Fumarase, class I, homodimeric; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.432 |
SDH80349.1 | SDI71304.1 | SAMN05216272_103189 | SAMN05216272_11728 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Aminomethyltransferase; Belongs to the GcvT family. | 0.842 |
SDH80349.1 | SDI71370.1 | SAMN05216272_103189 | SAMN05216272_11732 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Aminomethyltransferase; Belongs to the GcvT family. | 0.882 |
SDH80349.1 | folD-2 | SAMN05216272_103189 | SAMN05216272_11730 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.827 |
SDH80349.1 | purL | SAMN05216272_103189 | SAMN05216272_102154 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.426 |
SDH80349.1 | purU-3 | SAMN05216272_103189 | SAMN05216272_11729 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). | 0.755 |
SDI34808.1 | SDH80349.1 | SAMN05216272_10872 | SAMN05216272_103189 | Hypothetical protein. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.784 |
SDI34808.1 | SDI61595.1 | SAMN05216272_10872 | SAMN05216272_11314 | Hypothetical protein. | Sarcosine oxidase subunit delta. | 0.830 |
SDI34808.1 | SDI61633.1 | SAMN05216272_10872 | SAMN05216272_11316 | Hypothetical protein. | Sarcosine oxidase subunit gamma. | 0.840 |
SDI34808.1 | purU-3 | SAMN05216272_10872 | SAMN05216272_11729 | Hypothetical protein. | Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). | 0.717 |
SDI61595.1 | SDI34808.1 | SAMN05216272_11314 | SAMN05216272_10872 | Sarcosine oxidase subunit delta. | Hypothetical protein. | 0.830 |
SDI61595.1 | SDI61633.1 | SAMN05216272_11314 | SAMN05216272_11316 | Sarcosine oxidase subunit delta. | Sarcosine oxidase subunit gamma. | 0.999 |
SDI61595.1 | SDI71304.1 | SAMN05216272_11314 | SAMN05216272_11728 | Sarcosine oxidase subunit delta. | Aminomethyltransferase; Belongs to the GcvT family. | 0.873 |
SDI61595.1 | SDI71370.1 | SAMN05216272_11314 | SAMN05216272_11732 | Sarcosine oxidase subunit delta. | Aminomethyltransferase; Belongs to the GcvT family. | 0.885 |
SDI61595.1 | purU-3 | SAMN05216272_11314 | SAMN05216272_11729 | Sarcosine oxidase subunit delta. | Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). | 0.816 |
SDI61633.1 | SDI34808.1 | SAMN05216272_11316 | SAMN05216272_10872 | Sarcosine oxidase subunit gamma. | Hypothetical protein. | 0.840 |
SDI61633.1 | SDI61595.1 | SAMN05216272_11316 | SAMN05216272_11314 | Sarcosine oxidase subunit gamma. | Sarcosine oxidase subunit delta. | 0.999 |
SDI61633.1 | SDI71304.1 | SAMN05216272_11316 | SAMN05216272_11728 | Sarcosine oxidase subunit gamma. | Aminomethyltransferase; Belongs to the GcvT family. | 0.870 |
SDI61633.1 | SDI71370.1 | SAMN05216272_11316 | SAMN05216272_11732 | Sarcosine oxidase subunit gamma. | Aminomethyltransferase; Belongs to the GcvT family. | 0.889 |