STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
SKC67300.1L-proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. (1071 aa)    
Predicted Functional Partners:
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
   
 0.960
proB
Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
    
 0.949
proA
Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
    
 0.946
SKC58939.1
Dihydrolipoamide dehydrogenase.
  
 
 0.945
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
    
 0.943
SKC63755.1
PAS domain S-box-containing protein.
  
  
 0.939
SKC66619.1
L-glutamine synthetase.
   
 
 0.934
SKC78553.1
Glutamate--putrescine ligase; Belongs to the glutamine synthetase family.
   
 
 0.934
SKC78609.1
L-glutamine synthetase.
   
 
 0.934
SKC79890.1
Aldehyde dehydrogenase (NAD+); Belongs to the aldehyde dehydrogenase family.
 
0.933
Your Current Organism:
Pseudoxanthomonas indica
NCBI taxonomy Id: 428993
Other names: CCM 7430, MTCC 8596, P. indica, Pseudoxanthomonas indica Kumari et al. 2011, Pseudoxanthomonas sp. ES-4, Pseudoxanthomonas sp. P15, strain P15
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