node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SKC50515.1 | SKC64884.1 | SAMN06296058_0784 | SAMN06296058_1830 | Helicase conserved C-terminal domain-containing protein. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.971 |
SKC50515.1 | SKC75436.1 | SAMN06296058_0784 | SAMN06296058_2538 | Helicase conserved C-terminal domain-containing protein. | ATP-dependent DNA helicase RecQ. | 0.905 |
SKC50515.1 | SKC82017.1 | SAMN06296058_0784 | SAMN06296058_3587 | Helicase conserved C-terminal domain-containing protein. | Recombination protein MgsA. | 0.417 |
SKC50515.1 | polA | SAMN06296058_0784 | SAMN06296058_1712 | Helicase conserved C-terminal domain-containing protein. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.982 |
SKC54415.1 | SKC82017.1 | SAMN06296058_1047 | SAMN06296058_3587 | uroporphyrinogen-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | Recombination protein MgsA. | 0.422 |
SKC54415.1 | nadE-2 | SAMN06296058_1047 | SAMN06296058_2489 | uroporphyrinogen-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | NAD+ synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.402 |
SKC64884.1 | SKC50515.1 | SAMN06296058_1830 | SAMN06296058_0784 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Helicase conserved C-terminal domain-containing protein. | 0.971 |
SKC64884.1 | SKC75436.1 | SAMN06296058_1830 | SAMN06296058_2538 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | ATP-dependent DNA helicase RecQ. | 0.899 |
SKC64884.1 | SKC82017.1 | SAMN06296058_1830 | SAMN06296058_3587 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Recombination protein MgsA. | 0.617 |
SKC64884.1 | polA | SAMN06296058_1830 | SAMN06296058_1712 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.999 |
SKC75436.1 | SKC50515.1 | SAMN06296058_2538 | SAMN06296058_0784 | ATP-dependent DNA helicase RecQ. | Helicase conserved C-terminal domain-containing protein. | 0.905 |
SKC75436.1 | SKC64884.1 | SAMN06296058_2538 | SAMN06296058_1830 | ATP-dependent DNA helicase RecQ. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.899 |
SKC75436.1 | SKC82017.1 | SAMN06296058_2538 | SAMN06296058_3587 | ATP-dependent DNA helicase RecQ. | Recombination protein MgsA. | 0.849 |
SKC75436.1 | polA | SAMN06296058_2538 | SAMN06296058_1712 | ATP-dependent DNA helicase RecQ. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.984 |
SKC77520.1 | SKC82017.1 | SAMN06296058_2813 | SAMN06296058_3587 | methylated-DNA-[protein]-cysteine S-methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | Recombination protein MgsA. | 0.468 |
SKC81995.1 | SKC82017.1 | SAMN06296058_3585 | SAMN06296058_3587 | DNA translocase FtsK. | Recombination protein MgsA. | 0.546 |
SKC81995.1 | lolA | SAMN06296058_3585 | SAMN06296058_3586 | DNA translocase FtsK. | Outer membrane lipoprotein carrier protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). | 0.679 |
SKC81995.1 | polA | SAMN06296058_3585 | SAMN06296058_1712 | DNA translocase FtsK. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.714 |
SKC82017.1 | SKC50515.1 | SAMN06296058_3587 | SAMN06296058_0784 | Recombination protein MgsA. | Helicase conserved C-terminal domain-containing protein. | 0.417 |
SKC82017.1 | SKC54415.1 | SAMN06296058_3587 | SAMN06296058_1047 | Recombination protein MgsA. | uroporphyrinogen-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.422 |