close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Adeg_0899Signal transduction histidine kinase, LytS; PFAM: histidine kinase internal region; GAF domain protein; 5TM Receptors of the LytS-YhcK type transmembrane region; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; GAF domain protein; KEGG: gme:Gmet_2698 histidine kinase internal region. (572 aa)    
Predicted Functional Partners:
Adeg_0898
Two component transcriptional regulator, LytTR family; PFAM: response regulator receiver; LytTr DNA-binding region; SMART: response regulator receiver; KEGG: dde:Dde_0161 LytR/AlgR family transcriptional regulator.
 
 0.997
Adeg_1761
Two component transcriptional regulator, LytTR family; PFAM: response regulator receiver; LytTr DNA-binding region; SMART: response regulator receiver; KEGG: gme:Gmet_2697 LytR/AlgR family transcriptional regulator.
 
 0.988
Adeg_0897
PFAM: carbon starvation protein CstA; KEGG: dvm:DvMF_1227 carbon starvation protein CstA.
 
   
 0.651
Adeg_0900
PFAM: formyl transferase domain protein; KEGG: xcc:XCC2791 phosphoribosylglycinamide formyltransferase.
       0.530
Adeg_0901
Conserved hypothetical protein; KEGG: hch:HCH_05403 phosphoserine phosphatase SerB.
       0.530
Adeg_0902
PFAM: PfkB domain protein; KEGG: mxa:MXAN_3087 fructokinase; Belongs to the carbohydrate kinase PfkB family.
       0.513
Adeg_0903
PFAM: short-chain dehydrogenase/reductase SDR; KEGG: pca:Pcar_2044 enoyl-(acyl-carrier-protein) reductase (NADH-dependent).
       0.463
Your Current Organism:
Ammonifex degensii
NCBI taxonomy Id: 429009
Other names: A. degensii KC4, Ammonifex degensii KC4, Ammonifex degensii str. KC4, Ammonifex degensii strain KC4
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.