Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Adeg_0937TIGRFAM: precorrin-6x reductase; PFAM: Precorrin-6x reductase CbiJ/CobK; KEGG: tau:Tola_1672 precorrin-6x reductase. (255 aa)    
Predicted Functional Partners:
cbiD
Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
 
 0.999
Adeg_0932
TIGRFAM: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; KEGG: pca:Pcar_2739 precorrin-6Y C5,15-methyltransferase.
 
 0.999
Adeg_0936
TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: gme:Gmet_0485 cobyric acid synthase CobQ:precorrin-3B C17-methyltransferase region.
  
 0.999
Adeg_0935
PFAM: cobalamin (vitamin B12) biosynthesis CbiG protein; KEGG: dma:DMR_02540 cobalamin biosynthesis protein CbiG.
  
 0.997
Adeg_0934
KEGG: gur:Gura_0039 precorrin-4 C11-methyltransferase; TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family.
 
  
 0.995
Adeg_0933
TIGRFAM: precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: gem:GM21_3608 precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family.
 
  
 0.994
Adeg_0939
PFAM: Precorrin-8X methylmutase CbiC/CobH; KEGG: sfu:Sfum_2136 precorrin-8X methylmutase CbiC/CobH.
 
  
 0.994
cobQ
Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
  
 0.967
Adeg_1261
TIGRFAM: siroheme synthase; KEGG: sat:SYN_02276 precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase.
    
 0.931
Adeg_0938
PFAM: cobalamin (vitamin B12) biosynthesis CbiX protein; KEGG: gsu:GSU3000 CbiX protein.
 
   
 0.878
Your Current Organism:
Ammonifex degensii
NCBI taxonomy Id: 429009
Other names: A. degensii KC4, Ammonifex degensii KC4, Ammonifex degensii str. KC4, Ammonifex degensii strain KC4
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