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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Adeg_1027Integral membrane sensor signal transduction histidine kinase; KEGG: gsu:GSU1101 sensory box histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein. (473 aa)    
Predicted Functional Partners:
Adeg_1011
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: tbd:Tbd_0216 two component transcriptional regulator.
 
 0.983
Adeg_1028
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: vap:Vapar_2988 two component transcriptional regulator, winged helix family.
 
 0.971
Adeg_1482
PFAM: Osmosensitive K channel His kinase sensor; UspA domain protein; KEGG: mca:MCA2214 sensor histidine kinase KdpD.
 
 
 0.915
Adeg_1897
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: bxe:Bxe_B0815 two component transcriptional regulator.
 
 0.895
Adeg_0644
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: glo:Glov_0588 two component transcriptional regulator, winged helix family.
 
 0.890
Adeg_2021
KEGG: gbm:Gbem_0626 MCP methyltransferase, CheR-type; PFAM: MCP methyltransferase CheR-type; SMART: MCP methyltransferase CheR-type.
      0.792
Adeg_1034
Two component transcriptional regulator, LuxR family; PFAM: response regulator receiver; regulatory protein LuxR; Sigma-70 region 4 type 2; SMART: response regulator receiver; regulatory protein LuxR; KEGG: dat:HRM2_24220 TRAP-type C4-dicarboxylate transporter, periplasmic solute-binding protein.
 
 
 0.756
Adeg_2019
PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: mxa:MXAN_6693 fibril biogenesis regulator DifD.
 
   
 0.719
Adeg_1202
PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: ank:AnaeK_2309 response regulator receiver modulated diguanylate cyclase.
 
   
 0.684
Adeg_1040
PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: gbm:Gbem_1834 response regulator receiver protein.
 
   
 0.682
Your Current Organism:
Ammonifex degensii
NCBI taxonomy Id: 429009
Other names: A. degensii KC4, Ammonifex degensii KC4, Ammonifex degensii str. KC4, Ammonifex degensii strain KC4
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.