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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Adeg_1964PFAM: Circadian clock protein KaiC central region; KEGG: nis:NIS_1761 ATPase. (281 aa)    
Predicted Functional Partners:
Adeg_1482
PFAM: Osmosensitive K channel His kinase sensor; UspA domain protein; KEGG: mca:MCA2214 sensor histidine kinase KdpD.
   
 
 0.796
rgy
Reverse gyrase; Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication; In the C-terminal section; belongs to the prokaryotic type I/III topoisomerase family.
 
     0.762
bpsA
Protein of unknown function DUF43; Involved in the biosynthesis of branched-chain polyamines, which support the growth of thermophiles under high-temperature conditions. Catalyzes the sequential condensation of spermidine with the aminopropyl groups of decarboxylated S-adenosylmethionines to produce N(4)-bis(aminopropyl)spermidine via N(4)-aminopropylspermidine.
  
     0.722
Adeg_1670
PFAM: GCN5-related N-acetyltransferase; KEGG: hch:HCH_01993 histone acetyltransferase HPA2-like acetyltransferase.
  
     0.693
Adeg_1963
PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: ppd:Ppro_0724 methyl-accepting chemotaxis sensory transducer.
       0.551
Adeg_1201
KEGG: gur:Gura_1941 metal dependent phosphohydrolase; TIGRFAM: metal dependent phophohydrolase; PFAM: Transcriptional regulator, histidine kinase sensor-like; metal-dependent phosphohydrolase HD sub domain; GAF domain protein; Metal-dependent hydrolase HDOD; SMART: metal-dependent phosphohydrolase HD region; GAF domain protein.
     
 0.416
hslO
Hsp33 protein; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
  
     0.405
Your Current Organism:
Ammonifex degensii
NCBI taxonomy Id: 429009
Other names: A. degensii KC4, Ammonifex degensii KC4, Ammonifex degensii str. KC4, Ammonifex degensii strain KC4
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