Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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Adeg_2134Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (441 aa)    
Predicted Functional Partners:
Adeg_0874
Replicative DNA helicase-like protein; KEGG: lhk:LHK_01738 DnaB.
  
  
  0.946
Adeg_1373
Replicative DNA helicase-like protein; KEGG: lhk:LHK_01738 DnaB.
  
  
  0.942
rplI
Ribosomal protein L9; Binds to the 23S rRNA.
  
  
 0.858
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
 
 0.840
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
       0.774
Adeg_2133
PFAM: FAD dependent oxidoreductase; KEGG: sat:SYN_02917 FAD-dependent dehydrogenase.
       0.714
Adeg_1702
PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: hha:Hhal_0638 IstB ATP binding domain-containing protein.
  
 
 0.692
Adeg_2137
Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
 
 
 0.664
Adeg_0693
PFAM: zinc finger CHC2-family protein; TOPRIM domain protein; SMART: zinc finger CHC2-family protein; KEGG: gme:Gmet_0394 DNA primase.
 
 0.656
rpsR
Ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.
  
    0.655
Your Current Organism:
Ammonifex degensii
NCBI taxonomy Id: 429009
Other names: A. degensii KC4, Ammonifex degensii KC4, Ammonifex degensii str. KC4, Ammonifex degensii strain KC4
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