Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
rsmGMethyltransferase GidB; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family. (241 aa)    
Predicted Functional Partners:
Adeg_2148
PFAM: single-stranded nucleic acid binding R3H domain protein; SMART: single-stranded nucleic acid binding R3H domain protein; KEGG: sfu:Sfum_2598 single-stranded nucleic acid binding R3H domain-containing protein.
  
  
 0.897
Adeg_2145
KEGG: aeh:Mlg_2877 ParB-like partition proteins; TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease; SMART: ParB domain protein nuclease; Belongs to the ParB family.
  
  
 0.864
Adeg_2149
TIGRFAM: membrane protein insertase, YidC/Oxa1 family; PFAM: 60 kDa inner membrane insertion protein; KEGG: nam:NAMH_0842 inner membrane protein OxaA.
  
  
 0.839
Adeg_2146
PFAM: Cobyrinic acid ac-diamide synthase; KEGG: geo:Geob_0454 cobyrinic acid ac-diamide synthase.
  
  
 0.761
rnpA
Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
  
  
 0.757
rpmH
TIGRFAM: ribosomal protein L34; PFAM: ribosomal protein L34; KEGG: ank:AnaeK_4498 50S ribosomal protein L34; Belongs to the bacterial ribosomal protein bL34 family.
  
  
 0.755
Adeg_0746
PFAM: ParB domain protein nuclease; SMART: ParB domain protein nuclease; KEGG: Kelch motif family protein.
  
  
 0.748
Adeg_2150
Protein of unknown function DUF37; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family.
  
    0.678
Adeg_2143
Hypothetical protein.
     
 0.660
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
 0.647
Your Current Organism:
Ammonifex degensii
NCBI taxonomy Id: 429009
Other names: A. degensii KC4, Ammonifex degensii KC4, Ammonifex degensii str. KC4, Ammonifex degensii strain KC4
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