STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDL12_28534U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. (192 aa)    
Predicted Functional Partners:
CDL12_20224
Small nuclear ribonucleoprotein Sm D2.
   
 0.996
CDL12_10644
Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family.
   
 0.996
CDL12_24915
Small nuclear ribonucleoprotein (SnRNP) SMF.
   
 0.982
CDL12_20547
Small nuclear ribonucleoprotein (SnRNP) SMF.
   
 0.982
CDL12_10649
Small nuclear ribonucleoprotein Sm D3; Core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome.
   
 0.979
CDL12_07312
Small nuclear ribonucleoprotein Sm D3; Core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome.
   
 0.979
CDL12_24317
Small nuclear ribonucleoprotein G.
   
 0.978
CDL12_20155
Small nuclear ribonucleoprotein G.
   
 0.978
CDL12_27215
Small nuclear ribonucleoprotein-associated protein.
   
 0.977
CDL12_16752
Small nuclear ribonucleoprotein-associated protein.
   
 0.977
Your Current Organism:
Handroanthus impetiginosus
NCBI taxonomy Id: 429701
Other names: H. impetiginosus, Handroanthus impetiginosus (Mart. ex DC.) Mattos, Tabebuia impetiginosa, Tabebuia impetiginosa (Mart. ex DC.) Standl., Tabebuia palmeri, Tabebuia palmeri Rose
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