STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
COQ6Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. (435 aa)    
Predicted Functional Partners:
COQ3
Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.
 
 
 0.981
CDL12_11537
Methyltransferase.
   
 0.966
CDL12_28730
Uncharacterized protein.
   
 0.949
COQ5
2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2).
   
 0.949
CDL12_11835
Para-hydroxybenzoate-polyprenyl transferase.
  
  
 0.919
CDL12_02498
Ubiquinone biosynthesis protein; Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration.
   
 
 0.881
CDL12_15567
15-cis-phytoene synthase.
   
 
 0.808
CDL12_11293
Squalene synthetase.
   
 
 0.808
CDL12_30101
Sulfite oxidase, molybdopterin-binding component.
   
 0.792
CDL12_08293
NADH-cytochrome b-5 reductase.
   
 0.792
Your Current Organism:
Handroanthus impetiginosus
NCBI taxonomy Id: 429701
Other names: H. impetiginosus, Handroanthus impetiginosus (Mart. ex DC.) Mattos, Tabebuia impetiginosa, Tabebuia impetiginosa (Mart. ex DC.) Standl., Tabebuia palmeri, Tabebuia palmeri Rose
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