node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KKB08017.1 | KKB08394.1 | VE26_15635 | VE26_16500 | Dihydropyrimidinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Diguanylate cyclase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.856 |
KKB08017.1 | KKB09299.1 | VE26_15635 | VE26_04860 | Dihydropyrimidinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Dihydroorotase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.751 |
KKB08017.1 | KKB09624.1 | VE26_15635 | VE26_07025 | Dihydropyrimidinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Dihydroorotase; Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.467 |
KKB08017.1 | carA | VE26_15635 | VE26_10040 | Dihydropyrimidinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Carbamoyl-phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarA family. | 0.832 |
KKB08017.1 | carB | VE26_15635 | VE26_10165 | Dihydropyrimidinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Carbamoyl phosphate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarB family. | 0.843 |
KKB08017.1 | pyrB | VE26_15635 | VE26_07020 | Dihydropyrimidinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aspartate carbamoyltransferase catalytic subunit; Catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.989 |
KKB08017.1 | pyrE | VE26_15635 | VE26_04305 | Dihydropyrimidinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.791 |
KKB08017.1 | pyrF | VE26_15635 | VE26_14410 | Dihydropyrimidinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.757 |
KKB08394.1 | KKB08017.1 | VE26_16500 | VE26_15635 | Diguanylate cyclase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Dihydropyrimidinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.856 |
KKB08394.1 | KKB08848.1 | VE26_16500 | VE26_01945 | Diguanylate cyclase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Dihydroorotase; Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.985 |
KKB08394.1 | KKB09299.1 | VE26_16500 | VE26_04860 | Diguanylate cyclase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Dihydroorotase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.846 |
KKB08394.1 | KKB09624.1 | VE26_16500 | VE26_07025 | Diguanylate cyclase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Dihydroorotase; Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.970 |
KKB08394.1 | carA | VE26_16500 | VE26_10040 | Diguanylate cyclase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Carbamoyl-phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarA family. | 0.938 |
KKB08394.1 | carB | VE26_16500 | VE26_10165 | Diguanylate cyclase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Carbamoyl phosphate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarB family. | 0.979 |
KKB08394.1 | purA | VE26_16500 | VE26_12000 | Diguanylate cyclase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.755 |
KKB08394.1 | pyrB | VE26_16500 | VE26_07020 | Diguanylate cyclase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Aspartate carbamoyltransferase catalytic subunit; Catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.964 |
KKB08394.1 | pyrE | VE26_16500 | VE26_04305 | Diguanylate cyclase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.995 |
KKB08394.1 | pyrF | VE26_16500 | VE26_14410 | Diguanylate cyclase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.965 |
KKB08848.1 | KKB08394.1 | VE26_01945 | VE26_16500 | Dihydroorotase; Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides; Derived by automated computational analysis using gene prediction method: Protein Homology. | Diguanylate cyclase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.985 |
KKB08848.1 | KKB09299.1 | VE26_01945 | VE26_04860 | Dihydroorotase; Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides; Derived by automated computational analysis using gene prediction method: Protein Homology. | Dihydroorotase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.472 |