Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
A0A182JPR6Uncharacterized protein. (652 aa)    
Predicted Functional Partners:
A0A182K039
TPR_REGION domain-containing protein.
    
 0.704
A0A182K2G4
P53 domain-containing protein.
    
  0.587
A0A182JQS2
Uncharacterized protein.
    
 0.582
A0A182K6G6
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.580
A0A182JT56
Histone-lysine N-methyltransferase.
    
 0.573
A0A182K3Q3
PCI domain-containing protein.
    
 0.514
A0A182JRJ8
Uncharacterized protein.
    
  0.513
A0A182JTB3
Uncharacterized protein.
    
 0.512
A0A182JTB5
Histone-lysine N-methyltransferase, H3 lysine-79 specific.
    
 0.512
A0A182JRA7
VEFS-Box domain-containing protein.
    
 0.494
Your Current Organism:
Anopheles christyi
NCBI taxonomy Id: 43041
Other names: A. christyi
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