STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
A0A182JS642-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (443 aa)    
Predicted Functional Partners:
A0A182JNC6
Transket_pyr domain-containing protein.
 0.999
A0A182K007
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 0.999
A0A182JSU6
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
 
 0.998
A0A182K4T1
Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
    
 0.983
A0A182JXT6
Lipoyl-binding domain-containing protein.
  
 0.964
A0A182JRF2
L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.
   
 
 0.951
A0A182JVJ7
Lipoyl-binding domain-containing protein.
  
 0.950
A0A182KEH4
Uncharacterized protein.
  
 
 0.949
A0A182JTP5
Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
    
 0.939
A0A182JNJ4
Uncharacterized protein.
    
 0.936
Your Current Organism:
Anopheles christyi
NCBI taxonomy Id: 43041
Other names: A. christyi
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.