Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
A0A182JV50General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (500 aa)    
Predicted Functional Partners:
A0A182JP18
Uncharacterized protein.
    
 0.999
A0A182KEE0
Uncharacterized protein.
   
 0.999
A0A182KCD8
General transcription factor IIH subunit.
   
 0.998
A0A182K4B3
Helicase ATP-binding domain-containing protein.
    
 0.997
A0A182KFX4
RING-type domain-containing protein.
    
 0.996
A0A182K6S6
CYCLIN domain-containing protein; Belongs to the cyclin family.
   
 0.994
A0A182KCC6
Uncharacterized protein.
   
 0.990
A0A182KAI9
Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
    
 0.989
A0A182JZ14
Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.
    
 0.983
A0A182KDF6
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
    
 0.983
Your Current Organism:
Anopheles christyi
NCBI taxonomy Id: 43041
Other names: A. christyi
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