Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
A0A182JW34Uncharacterized protein. (132 aa)    
Predicted Functional Partners:
A0A182K6G6
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.783
A0A182JQQ5
TAFII55_N domain-containing protein.
    
 
 0.709
A0A182JR06
Uncharacterized protein.
    
 
 0.687
A0A182K6A5
Uncharacterized protein.
    
 
 0.654
A0A182JXP6
Histone H2B; Belongs to the histone H2B family.
    
  0.647
A0A182K2H0
DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.
    
 
 0.634
A0A182JYK5
RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.
    
 
 0.628
A0A182JUW2
Uncharacterized protein.
    
 
 0.612
A0A182K3C8
DNA helicase; Belongs to the RuvB family.
    
 
 0.606
A0A182K466
PHD-type domain-containing protein.
   
 
 0.569
Your Current Organism:
Anopheles christyi
NCBI taxonomy Id: 43041
Other names: A. christyi
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