STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A182JYZ9Structure-specific endonuclease subunit SLX1 homolog; Catalytic subunit of a heterodimeric structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA; Belongs to the SLX1 family. (342 aa)    
Predicted Functional Partners:
A0A182JXC6
Uncharacterized protein.
    
 0.988
A0A182JRC5
Uncharacterized protein.
   
 0.977
A0A182JUP6
AA_TRNA_LIGASE_II domain-containing protein.
   
 0.954
A0A182K4E5
Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family.
    
 
 0.954
A0A182JUP8
Uncharacterized protein.
    
 0.918
A0A182JP47
Uncharacterized protein.
    
 0.890
A0A182JZN3
ERCC4 domain-containing protein.
   
 0.874
A0A182K9T2
ERCC4 domain-containing protein.
   
 0.871
A0A182JZF9
Toprim domain-containing protein.
    
 0.868
A0A182K5H1
Uncharacterized protein.
   
 0.862
Your Current Organism:
Anopheles christyi
NCBI taxonomy Id: 43041
Other names: A. christyi
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