Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
A0A182K238DEK_C domain-containing protein. (633 aa)    
Predicted Functional Partners:
A0A182JXI3
Uncharacterized protein.
    
 
 0.938
A0A182JPZ1
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
    
 
 0.922
A0A182KJ83
Daxx-like protein.
    
 
 0.868
A0A182K770
Uncharacterized protein.
   
 
 0.867
A0A182JZH9
Uncharacterized protein.
    
 
 0.858
A0A182K6G6
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
  0.830
A0A182K7B2
Uncharacterized protein.
    
 0.818
A0A182JXN9
FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]
   
   0.815
A0A182KE78
Uncharacterized protein.
    
 
 0.813
A0A182JVQ7
Aminotran_1_2 domain-containing protein.
    
   0.811
Your Current Organism:
Anopheles christyi
NCBI taxonomy Id: 43041
Other names: A. christyi
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