Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
A0A182K2S2ADF-H domain-containing protein. (146 aa)    
Predicted Functional Partners:
A0A182JXA9
Uncharacterized protein.
   
 
 0.858
A0A182JWA5
F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
   
 0.857
A0A182JUM1
Uncharacterized protein.
    
 
 0.841
A0A182K896
Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.
   
 
 0.799
A0A182KEQ7
BAR domain-containing protein.
   
 
 0.791
A0A182JWB5
Adenylyl cyclase-associated protein; Belongs to the CAP family.
   
 
 0.766
A0A182KEJ8
Uncharacterized protein.
   
 
 0.766
A0A182JVP8
Uncharacterized protein.
   
 
 0.731
A0A182KAF0
Uncharacterized protein; Belongs to the actin family.
   
 
 0.678
A0A182JUB4
WH2 domain-containing protein.
   
 
 0.665
Your Current Organism:
Anopheles christyi
NCBI taxonomy Id: 43041
Other names: A. christyi
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