STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFE57425.12',3'-cyclic-nucleotide 2'-phosphodiesterase/5'-or 3'-nucleotidase, 5'-nucleotidase family; Belongs to the 5'-nucleotidase family. (462 aa)    
Predicted Functional Partners:
guaB
IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.943
cinA
Nicotinamide-nucleotide amidase; Belongs to the CinA family.
   
 
  0.882
guaA
GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP.
    
 0.878
SFE25380.1
Nicotinamide-nucleotide adenylyltransferase, NadR type.
     
 0.872
SFE06523.1
tRNA(Ile)-lysidine synthase TilS/MesJ; Belongs to the TtcA family.
    
 0.829
SFE57396.1
Uncharacterized protein YutD.
  
    0.822
SFE31661.1
Purine-nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
  
 
 0.795
deoD
Purine-nucleoside phosphorylase.
    
 0.764
SFE57365.1
4-nitrophenyl phosphatase.
  
  
 0.730
SFE57455.1
Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.
   
   0.695
Your Current Organism:
Trichococcus pasteurii
NCBI taxonomy Id: 43064
Other names: ATCC 35945, CCUG 37395, CIP 104580, DSM 2381, Lactosphaera pasteurii, Ruminococcus pasteurii, T. pasteurii, strain KoTa2
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