STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFE60077.1D-lactate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (323 aa)    
Predicted Functional Partners:
SFE31811.1
Pyruvate kinase; Belongs to the pyruvate kinase family.
 
 0.943
SFE10199.1
Pyruvate kinase; Belongs to the pyruvate kinase family.
 
 0.941
SFE40539.1
Acetaldehyde dehydrogenase / alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 
 0.910
SFE25708.1
Pyruvate-ferredoxin/flavodoxin oxidoreductase.
    
  0.885
SFE28639.1
Acetolactate synthase, large subunit.
  
 
 0.874
SFE93228.1
Glyoxylase, beta-lactamase superfamily II.
  
 0.871
SFE38050.1
Pyruvate dehydrogenase E1 component beta subunit.
  
 
 0.867
SFE44950.1
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
   
 
 0.865
pdhA
Pyruvate dehydrogenase E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
  
 
 0.863
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
  
 0.858
Your Current Organism:
Trichococcus pasteurii
NCBI taxonomy Id: 43064
Other names: ATCC 35945, CCUG 37395, CIP 104580, DSM 2381, Lactosphaera pasteurii, Ruminococcus pasteurii, T. pasteurii, strain KoTa2
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.