Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pepACytosol aminopeptidase PepA (EC 3.4.11.1); Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. (502 aa)    
Predicted Functional Partners:
FLM9_969
Cysteine synthase (EC 2.5.1.47); Belongs to the cysteine synthase/cystathionine beta- synthase family.
    
  0.854
FLM9_811
Aspartate aminotransferase (EC 2.6.1.1).
    
  0.853
glyA
Serine hydroxymethyltransferase (EC 2.1.2.1); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.837
FLM9_675
Carboxylate-amine ligase bll3764; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
     
  0.823
FLM9_367
Cyanobacteria-specific protein containing UvrC-like endonuclease domain.
       0.697
FLM9_368
Sll1386 protein.
       0.592
tyrS
Tyrosyl-tRNA synthetase (EC 6.1.1.1); Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
     
 0.578
FLM9_369
FIG020308: hypothetical protein.
       0.572
FLM9_579
5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
     
 0.567
pyrF
Orotidine 5'-phosphate decarboxylase (EC 4.1.1.23); Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
       0.540
Your Current Organism:
Synechococcus spongiarum
NCBI taxonomy Id: 431041
Other names: C. Synechococcus spongiarum, Candidatus Synechococcus spongiarum
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