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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pepACytosol aminopeptidase PepA (EC 3.4.11.1); Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. (502 aa)    
Predicted Functional Partners:
FLM9_969
Cysteine synthase (EC 2.5.1.47); Belongs to the cysteine synthase/cystathionine beta- synthase family.
    
 0.872
glyA
Serine hydroxymethyltransferase (EC 2.1.2.1); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.863
FLM9_811
Aspartate aminotransferase (EC 2.6.1.1).
    
  0.862
FLM9_367
Cyanobacteria-specific protein containing UvrC-like endonuclease domain.
       0.621
FLM9_368
Sll1386 protein.
       0.592
FLM9_579
5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
     
 0.497
FLM9_369
FIG020308: hypothetical protein.
       0.482
FLM9_773
Cysteine desulfurase (EC 2.8.1.7).
  
 
 0.477
FLM9_694
FIG01149718: hypothetical protein.
  
 
 0.460
pyrF
Orotidine 5'-phosphate decarboxylase (EC 4.1.1.23); Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
       0.437
Your Current Organism:
Synechococcus spongiarum
NCBI taxonomy Id: 431041
Other names: C. Synechococcus spongiarum, Candidatus Synechococcus spongiarum
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