STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
sor5FAD-dependent monooxygenase sor5; FAD-dependent monooxygenase; part of the SOR gene cluster that mediates the biosynthesis of sorbicillinoids, a diverse group of yellow secondary metabolites that restrict growth of competing pathogenic fungi but not of bacteria. Sorbicillinoids biosynthesis requires the action of two PKSs. The SOR cluster is required for the production of trichodimerol and dihydrotrichotetronin, with sor2 being sufficient for production of trichodimerol, but not dihydrotrichotetronin in the light. Sor1 iteratively combines three acetyl units and the growing chain is mo [...] (456 aa)    
Predicted Functional Partners:
sor7
Short chain dehydrogenase sor7; Short chain dehydrogenase; part of the SOR gene cluster that mediates the biosynthesis of sorbicillinoids, a diverse group of yellow secondary metabolites that restrict growth of competing pathogenic fungi but not of bacteria. Sorbicillinoids biosynthesis requires the action of two PKSs. The SOR cluster is required for the production of trichodimerol and dihydrotrichotetronin, with sor2 being sufficient for production of trichodimerol, but not dihydrotrichotetronin in the light. Sor1 iteratively combines three acetyl units and the growing chain is modifi [...]
     
 0.594
sor3
Sorbicillinoid biosynthetic cluster transcription factor sor3; Transcription factor that acts in concert with sor4 which is a transcriptional activator of the gene cluster that mediates the biosynthesis of sorbicillinoids, a diverse group of yellow secondary metabolites that restrict growth of competing pathogenic fungi but not of bacteria. Regulates the cluster genes in a light dependent manner. Plays also a direct or indirect role in regulation of paracelsin biosynthesis and cellulase gene expression.
      
 0.567
sor2
Non-reducing polyketide synthase sor2; Non-reducing polyketide synthase; part of the SOR gene cluster that mediates the biosynthesis of sorbicillinoids, a diverse group of yellow secondary metabolites that restrict growth of competing pathogenic fungi but not of bacteria. Sorbicillinoids biosynthesis requires the action of two PKSs. The SOR cluster is required for the production of trichodimerol and dihydrotrichotetronin, with sor2 being sufficient for production of trichodimerol, but not dihydrotrichotetronin in the light. Sor1 iteratively combines three acetyl units and the growing c [...]
 
    
 0.566
sor1
Highly reducing polyketide synthase sor1; Highly reducing polyketide synthase; part of the SOR gene cluster that mediates the biosynthesis of sorbicillinoids, a diverse group of yellow secondary metabolites that restrict growth of competing pathogenic fungi but not of bacteria. Sorbicillinoids biosynthesis requires the action of two PKSs. The SOR cluster is required for the production of trichodimerol and dihydrotrichotetronin, with sor2 being sufficient for production of trichodimerol, but not dihydrotrichotetronin in the light. Sor1 iteratively combines three acetyl units and the gro [...]
      
 0.565
sor4
Sorbicillinoid biosynthetic cluster transcription factor sor4; Transcription factor that acts as the main regulator of the gene cluster that mediates the biosynthesis of sorbicillinoids, a diverse group of yellow secondary metabolites that restrict growth of competing pathogenic fungi but not of bacteria.
      
 0.565
sor6
Major facilitator-type transporter sor6; Major facilitator-type transporter; part of the gene cluster that mediates the biosynthesis of sorbicillinoids, a diverse group of yellow secondary metabolites that restrict growth of competing pathogenic fungi but not of bacteria. Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
      
 0.564
BNA5
Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.
  
 
 0.501
G0RGR1_HYPJQ
Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family.
   
 
 0.427
Your Current Organism:
Trichoderma reesei
NCBI taxonomy Id: 431241
Other names: T. reesei QM6a, Trichoderma reesei QM6a
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