STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pdhA-2Pyruvate dehydrogenase E1 component subunit alpha. (321 aa)    
Predicted Functional Partners:
pdhB
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 0.999
pdhB-2
Pyruvate dehydrogenase E1 component subunit beta; Transketolase-like, pyrimidine-binding domain.
 0.999
lpd
Dihydrolipoamide dehydrogenase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
  
 0.989
acoC-2
Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase); Alpha/beta hydrolase fold-1.
 
 0.983
pdhC
Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.956
acoC
Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase); Alpha/beta hydrolase fold-1.
 
 0.900
tal
Glucose-6-phosphate isomerase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the GPI family.
  
 
 0.824
sucB
2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase); E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
 
 0.815
pdhD
Dihydrolipoamide dehydrogenase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
 
 
 0.814
gcd-2
Quinoprotein glucose dehydrogenase; PQQ-dependent enzyme, N-terminal.
    
  0.647
Your Current Organism:
Acetobacter ghanensis
NCBI taxonomy Id: 431306
Other names: A. ghanensis, Acetobacter ghanensis Cleenwerck et al. 2007, Acetobacter sp. 384, Acetobacter sp. 444B, DSM 18895, LMG 23848, LMG:23848, strain 430A, strain R-29337
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