Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cobHprecorrin-8X methylmutase. (209 aa)    
Predicted Functional Partners:
cobL
precorrin-6Y C5,15-methyltransferase / precorrin-8W decarboxylase.
 
 
 0.998
cobJ
precorrin-3B C17-methyltransferase.
  
 0.998
cobI
Precorrin-2 C20-methyltransferase / cobalt-factor-2 C20-methyltransferase; [EC:2.1.1.130 2.1.1.151]; Belongs to the precorrin methyltransferase family.
 
 
 0.998
cobB
Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
 
 0.993
cobK
precorrin-6X reductase.
 
 
 0.990
cobM
Precorrin-4 C11-methyltransferase; Belongs to the precorrin methyltransferase family.
 
 
 0.989
cobG
precorrin-3B synthase; [EC:1.14.13.83]; cobalamin(vitamin B12) biosynthesis protein precorrin-3B.
 
 0.980
cobQ
Adenosylcobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
  
 0.976
cobN
Cobaltochelatase CobN.
 
  
 0.864
cbiD
Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
 
  
 0.854
Your Current Organism:
Acetobacter ghanensis
NCBI taxonomy Id: 431306
Other names: A. ghanensis, Acetobacter ghanensis Cleenwerck et al. 2007, Acetobacter sp. 384, Acetobacter sp. 444B, DSM 18895, LMG 23848, LMG:23848, strain 430A, strain R-29337
Server load: medium (56%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.