Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
tcrXSignal transduction response regulator, receiver domain. (249 aa)    
Predicted Functional Partners:
dos-2
Sensory box protein.
  
 0.941
pleD
Hypothetical protein; Diguanylate cyclase, predicted.
  
 
 0.900
AGA_1487
Two-component system, NtrC family, sensor kinase.
 
 0.870
AGA_1937
Signal transduction histidine kinase; ATPase-like, ATP-binding domain.
 
  
 0.861
AGA_1488
PAS/PAC sensor hybrid histidine kinase; ATPase-like, ATP-binding domain.
 
 0.859
rpoE-2
RNA polymerase, sigma-24 subunit, ECF subfamily; Belongs to the sigma-70 factor family. ECF subfamily.
 
     0.848
AGA_72
Putative phage protein; GGDEF: diguanylate cyclase (GGDEF) domain; PHAST result (e-value 1e-18).
  
 0.842
cheA
Two-component system, chemotaxis family, sensor kinase CheA; ATPase-like, ATP-binding domain.
  
 0.812
cckA
Sensory box histidine kinase/response regulator; ATPase-like, ATP-binding domain.
  
 0.796
rpoE
ECF subfamily RNA polymerase sigma-24 factor; Belongs to the sigma-70 factor family. ECF subfamily.
 
     0.783
Your Current Organism:
Acetobacter ghanensis
NCBI taxonomy Id: 431306
Other names: A. ghanensis, Acetobacter ghanensis Cleenwerck et al. 2007, Acetobacter sp. 384, Acetobacter sp. 444B, DSM 18895, LMG 23848, LMG:23848, strain 430A, strain R-29337
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