| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| carA | carB | AGA_1451 | AGA_1450 | Carbamoyl-phosphate synthase small subunit; Belongs to the CarA family. | Carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. | 0.999 |
| carA | glmS | AGA_1451 | AGA_2027 | Carbamoyl-phosphate synthase small subunit; Belongs to the CarA family. | Glucosamine-fructose-6-phosphate aminotransferase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.900 |
| carA | glnA | AGA_1451 | AGA_1126 | Carbamoyl-phosphate synthase small subunit; Belongs to the CarA family. | Glutamine synthetase. | 0.939 |
| carA | gltS | AGA_1451 | AGA_2346 | Carbamoyl-phosphate synthase small subunit; Belongs to the CarA family. | [EC:1.4.7.1]; glutamate synthase (NADPH) large subunit (EC:1.4.1.13). | 0.958 |
| carA | purF | AGA_1451 | AGA_211 | Carbamoyl-phosphate synthase small subunit; Belongs to the CarA family. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.955 |
| carB | carA | AGA_1450 | AGA_1451 | Carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. | Carbamoyl-phosphate synthase small subunit; Belongs to the CarA family. | 0.999 |
| carB | glmS | AGA_1450 | AGA_2027 | Carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. | Glucosamine-fructose-6-phosphate aminotransferase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.929 |
| carB | glnA | AGA_1450 | AGA_1126 | Carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. | Glutamine synthetase. | 0.947 |
| carB | gltS | AGA_1450 | AGA_2346 | Carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. | [EC:1.4.7.1]; glutamate synthase (NADPH) large subunit (EC:1.4.1.13). | 0.979 |
| carB | purF | AGA_1450 | AGA_211 | Carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.983 |
| carB | tal | AGA_1450 | AGA_950 | Carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. | Glucose-6-phosphate isomerase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the GPI family. | 0.494 |
| glmM | glmS | AGA_416 | AGA_2027 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | Glucosamine-fructose-6-phosphate aminotransferase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.974 |
| glmM | glmU | AGA_416 | AGA_2026 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | Bifunctional protein GlmU; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.984 |
| glmM | manC | AGA_416 | AGA_1014 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | Mannose-6-phosphate isomerase; Belongs to the mannose-6-phosphate isomerase type 2 family. | 0.957 |
| glmM | nagA | AGA_416 | AGA_537 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | N-acetylglucosamine-6-phosphate deacetylase. | 0.901 |
| glmM | tal | AGA_416 | AGA_950 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | Glucose-6-phosphate isomerase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the GPI family. | 0.933 |
| glmS | carA | AGA_2027 | AGA_1451 | Glucosamine-fructose-6-phosphate aminotransferase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Carbamoyl-phosphate synthase small subunit; Belongs to the CarA family. | 0.900 |
| glmS | carB | AGA_2027 | AGA_1450 | Glucosamine-fructose-6-phosphate aminotransferase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. | 0.929 |
| glmS | glmM | AGA_2027 | AGA_416 | Glucosamine-fructose-6-phosphate aminotransferase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.974 |
| glmS | glmU | AGA_2027 | AGA_2026 | Glucosamine-fructose-6-phosphate aminotransferase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Bifunctional protein GlmU; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.983 |