| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AGA_2130 | lolA | AGA_2130 | AGA_2128 | Ribosomal RNA small subunit methyltransferase E; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | Outer membrane lipoprotein carrier protein LolA; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). | 0.464 |
| AGA_2130 | ubiA | AGA_2130 | AGA_2129 | Ribosomal RNA small subunit methyltransferase E; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | 4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.622 |
| AGA_2322 | ubiA | AGA_2322 | AGA_2129 | Hypothetical protein. | 4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.695 |
| atpE | ubiA | AGA_221 | AGA_2129 | Hypothetical protein predicted by Glimmer/Critica; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. | 4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.586 |
| etf | ispA | AGA_373 | AGA_1777 | Electron-transferring-flavoprotein dehydrogenase; Accepts electrons from ETF and reduces ubiquinone. | Geranyltranstransferase; Belongs to the FPP/GGPP synthase family. | 0.693 |
| etf | ispB | AGA_373 | AGA_1536 | Electron-transferring-flavoprotein dehydrogenase; Accepts electrons from ETF and reduces ubiquinone. | Octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | 0.693 |
| etf | ubiA | AGA_373 | AGA_2129 | Electron-transferring-flavoprotein dehydrogenase; Accepts electrons from ETF and reduces ubiquinone. | 4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.823 |
| etf | ubiG | AGA_373 | AGA_1597 | Electron-transferring-flavoprotein dehydrogenase; Accepts electrons from ETF and reduces ubiquinone. | 3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.465 |
| etf | ubiH-2 | AGA_373 | AGA_2161 | Electron-transferring-flavoprotein dehydrogenase; Accepts electrons from ETF and reduces ubiquinone. | Ubiquinone biosynthesis hydroxylase UbiH/UbiF/VisC/COQ6. | 0.466 |
| ispA | etf | AGA_1777 | AGA_373 | Geranyltranstransferase; Belongs to the FPP/GGPP synthase family. | Electron-transferring-flavoprotein dehydrogenase; Accepts electrons from ETF and reduces ubiquinone. | 0.693 |
| ispA | ispB | AGA_1777 | AGA_1536 | Geranyltranstransferase; Belongs to the FPP/GGPP synthase family. | Octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | 0.893 |
| ispA | ispG | AGA_1777 | AGA_1600 | Geranyltranstransferase; Belongs to the FPP/GGPP synthase family. | (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. | 0.462 |
| ispA | ubiA | AGA_1777 | AGA_2129 | Geranyltranstransferase; Belongs to the FPP/GGPP synthase family. | 4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.685 |
| ispB | etf | AGA_1536 | AGA_373 | Octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | Electron-transferring-flavoprotein dehydrogenase; Accepts electrons from ETF and reduces ubiquinone. | 0.693 |
| ispB | ispA | AGA_1536 | AGA_1777 | Octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | Geranyltranstransferase; Belongs to the FPP/GGPP synthase family. | 0.893 |
| ispB | ubiA | AGA_1536 | AGA_2129 | Octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | 4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.945 |
| ispG | ispA | AGA_1600 | AGA_1777 | (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. | Geranyltranstransferase; Belongs to the FPP/GGPP synthase family. | 0.462 |
| ispG | ubiA | AGA_1600 | AGA_2129 | (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. | 4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.595 |
| lolA | AGA_2130 | AGA_2128 | AGA_2130 | Outer membrane lipoprotein carrier protein LolA; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). | Ribosomal RNA small subunit methyltransferase E; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | 0.464 |
| lolA | ubiA | AGA_2128 | AGA_2129 | Outer membrane lipoprotein carrier protein LolA; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). | 4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.628 |