STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ntrCTwo-component system, NtrC family, nitrogen regulation response regulator GlnG; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes. (480 aa)    
Predicted Functional Partners:
ntrB
Two-component system, NtrC family, nitrogen regulation sensor histidine kinase GlnL; [EC:2.7.13.3]; two component sensor histidine kinase NtrB.
 0.994
ntrY
Two-component system, NtrC family, nitrogen regulation sensor histidine kinase NtrY; Multi-sensor signal transduction histidine kinase.
 
 0.968
cckA
Sensory box histidine kinase/response regulator; ATPase-like, ATP-binding domain.
 
 0.905
ntrX
Two-component system, NtrC family, nitrogen regulation response regulator NtrX.
 
   
0.832
AGA_1487
Two-component system, NtrC family, sensor kinase.
 
 
 0.811
pleD
Hypothetical protein; Diguanylate cyclase, predicted.
  
 0.805
AGA_1488
PAS/PAC sensor hybrid histidine kinase; ATPase-like, ATP-binding domain.
 
 0.742
AGA_2592
Metal dependent phosphohydrolase.
  
 0.733
hfq
Host factor-I protein; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.
   
 0.706
dos-2
Sensory box protein.
  
 0.678
Your Current Organism:
Acetobacter ghanensis
NCBI taxonomy Id: 431306
Other names: A. ghanensis, Acetobacter ghanensis Cleenwerck et al. 2007, Acetobacter sp. 384, Acetobacter sp. 444B, DSM 18895, LMG 23848, LMG:23848, strain 430A, strain R-29337
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