STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
amtBAmmonium transporter. (466 aa)    
Predicted Functional Partners:
glnB
Nitrogen regulatory protein PII; Belongs to the P(II) protein family.
 0.998
glnK
Nitrogen regulatory protein PII; Belongs to the P(II) protein family.
 0.998
gltS
[EC:1.4.7.1]; glutamate synthase (NADPH) large subunit (EC:1.4.1.13).
 
  
 0.787
ntrB
Two-component system, NtrC family, nitrogen regulation sensor histidine kinase GlnL; [EC:2.7.13.3]; two component sensor histidine kinase NtrB.
  
 
 0.738
AGA_2186
peptidyl-tRNA hydrolase domain protein; Class I peptide chain release factor.
       0.590
gltD
Glutamate synthase (NADPH/NADH) small chain; [EC:1.4.1.13 1.4.1.14].
 
  
 0.547
glnA
Glutamine synthetase.
  
  
 0.510
nadE
NAD+ synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
     
 0.507
AGA_1488
PAS/PAC sensor hybrid histidine kinase; ATPase-like, ATP-binding domain.
   
 0.500
glnD
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
     
 0.491
Your Current Organism:
Acetobacter ghanensis
NCBI taxonomy Id: 431306
Other names: A. ghanensis, Acetobacter ghanensis Cleenwerck et al. 2007, Acetobacter sp. 384, Acetobacter sp. 444B, DSM 18895, LMG 23848, LMG:23848, strain 430A, strain R-29337
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