STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sdhBSuccinate dehydrogenase; Ferredoxin domain; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (260 aa)    
Predicted Functional Partners:
sdhC
Succinate dehydrogenase/Fumarate reductase, transmembrane subunit.
 
 0.999
sdhD
Succinate dehydrogenase/Fumarate reductase, transmembrane subunit.
 
 0.999
sdhA
Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
 
 0.999
fumA
Fumarate hydratase, class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
 
 0.991
lpd
Dihydrolipoamide dehydrogenase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
  
 0.979
fumC
Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 0.962
petA
Ubiquinol-cytochrome c reductase iron-sulfur subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
 
 0.961
nuoI
NADH dehydrogenase I subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
   
 
 0.943
nouE
NADH dehydrogenase I subunit E.
   
 
 0.941
cyaC
Cytochrome o ubiquinol oxidase subunit III.
   
 
 0.926
Your Current Organism:
Acetobacter ghanensis
NCBI taxonomy Id: 431306
Other names: A. ghanensis, Acetobacter ghanensis Cleenwerck et al. 2007, Acetobacter sp. 384, Acetobacter sp. 444B, DSM 18895, LMG 23848, LMG:23848, strain 430A, strain R-29337
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.