pfkB protein (Acetobacter ghanensis) - STRING interaction network

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pfkB

Fructokinase; Carbohydrate/purine kinase. (332 aa)

Predicted Functional Partners:

tal

0.942

manC

0.928

guaA

0.923

purA

0.895

apt

0.845

guaB

0.827

hisA

0.780

hisA-2

0.780

rpe

0.763

AGA_1952

0.746

Your Current Organism:

Acetobacter ghanensis

NCBI taxonomy Id: 431306
Other names: A. ghanensis, Acetobacter ghanensis Cleenwerck et al. 2007, Acetobacter sp. 384, Acetobacter sp. 444B, DSM 18895, LMG 23848, LMG:23848, strain 430A, strain R-29337

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGA_1952	pfkB	AGA_1952	AGA_634	Xylose isomerase domain protein TIM barrel.	Fructokinase; Carbohydrate/purine kinase.	0.746
apt	guaA	AGA_575	AGA_970	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP.	0.976
apt	guaB	AGA_575	AGA_1823	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.888
apt	pfkB	AGA_575	AGA_634	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	Fructokinase; Carbohydrate/purine kinase.	0.845
apt	purA	AGA_575	AGA_829	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	0.814
apt	tal	AGA_575	AGA_950	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	Glucose-6-phosphate isomerase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the GPI family.	0.532
guaA	apt	AGA_970	AGA_575	GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP.	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	0.976
guaA	guaB	AGA_970	AGA_1823	GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP.	IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.999
guaA	hisA	AGA_970	AGA_452	GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP.	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.	0.904
guaA	hisA-2	AGA_970	AGA_453	GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP.	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Fusion protein [acetyltransferase and histidine biosynthesis HisA].	0.904
guaA	pfkB	AGA_970	AGA_634	GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP.	Fructokinase; Carbohydrate/purine kinase.	0.923
guaA	purA	AGA_970	AGA_829	GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP.	Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	0.931
guaA	rpe	AGA_970	AGA_1329	GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP.	Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.	0.590
guaA	tal	AGA_970	AGA_950	GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP.	Glucose-6-phosphate isomerase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the GPI family.	0.504
guaB	apt	AGA_1823	AGA_575	IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	0.888
guaB	guaA	AGA_1823	AGA_970	IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP.	0.999
guaB	pfkB	AGA_1823	AGA_634	IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	Fructokinase; Carbohydrate/purine kinase.	0.827
guaB	purA	AGA_1823	AGA_829	IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	0.988
guaB	tal	AGA_1823	AGA_950	IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	Glucose-6-phosphate isomerase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the GPI family.	0.608
hisA	guaA	AGA_452	AGA_970	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.	GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP.	0.904

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