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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Knowledge-based Evidence
from curated databases
textmining
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
thiE-2Thiamine-phosphate pyrophosphorylase. (194 aa)    
Predicted Functional Partners:
thiD
Phosphomethylpyrimidine kinase.
  
 
 0.974
thiG
Thiamine biosynthesis ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
  
 
 0.907
thiC
Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
  
 
 0.885
thiS
Thiamine biosynthesis ThiS; ThiamineS.
  
 
 0.879
thiE
Thiamine-phosphate pyrophosphorylase.
     
  0.868
AGA_781
Hypothetical protein.
       0.715
fbaB
Fructose-bisphosphate aldolase, class I.
       0.715
AGA_278
Protein of unknown function DUF448.
  
     0.675
moeB
UBA/ThiF-type NAD/FAD binding protein.
  
 
 0.661
thiL
Thiamine-monophosphate kinase.
  
 
 0.648
Your Current Organism:
Acetobacter ghanensis
NCBI taxonomy Id: 431306
Other names: A. ghanensis, Acetobacter ghanensis Cleenwerck et al. 2007, Acetobacter sp. 384, Acetobacter sp. 444B, DSM 18895, LMG 23848, LMG:23848, strain 430A, strain R-29337
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