STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AND_006400Insulin receptor. (1096 aa)    
Predicted Functional Partners:
AND_006817
Insulin-like peptide 2.
    
 0.938
AND_009176
Phosphatidylinositol 3-kinase regulatory subunit.
    
 0.933
AND_002117
Tyrosine phosphatase, non-receptor type nt1.
    
 0.932
AND_006349
IRS-type PTB domain-containing protein.
    
 0.919
AND_001767
Uncharacterized protein.
    
 0.919
AND_009681
Signal transduction protein lnk-realted.
    
 0.915
AND_003032
ENTH domain-containing protein.
    
  0.888
AND_001760
Unc-89 protein.
   
 0.857
AND_001557
Shc transforming protein.
    
 0.846
AND_001548
Shc transforming protein.
    
 0.846
Your Current Organism:
Anopheles darlingi
NCBI taxonomy Id: 43151
Other names: A. darlingi, American malaria mosquito, Anopheles paulistensis, Nyssorhynchus darlingi
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.