STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AND_000859Polypyrimidine tract binding protein. (730 aa)    
Predicted Functional Partners:
AND_007976
Heterogeneous nuclear ribonucleoprotein L.
   
 0.927
AND_010434
Heterogeneous nuclear ribonucleoprotein.
   
 0.897
AND_010188
Heterogeneous nuclear ribonucleoprotein k.
   
 0.894
AND_005255
Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing and RNA-mediated gene silencing (RNAi). The CBC complex is involved in miRNA-mediated RNA interference and is required for primary microRNAs (miRNAs) processing. Also involved in innate immunity via the short interfering RNAs (siRNAs) processing machinery by restricting the viral RNA production. In the CBC complex, Cbp20 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requ [...]
    
 0.822
AND_005730
Putative serine/arginine rich splicing factor.
   
 0.804
AND_001022
G-rich sequence factor-1.
   
 0.802
AND_002208
Putative arginine/serine-rich splicing factor.
   
 0.797
AND_010346
Poly(RC)-binding protein 3.
   
 0.775
AND_006427
RNA-binding protein 5.
    
 0.768
AND_002167
Far upstream (Fuse) binding protein.
   
 
 0.760
Your Current Organism:
Anopheles darlingi
NCBI taxonomy Id: 43151
Other names: A. darlingi, American malaria mosquito, Anopheles paulistensis, Nyssorhynchus darlingi
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.