node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AND_000270 | AND_001804 | W5JWD8 | W5JTZ8 | HD domain-containing protein. | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. | 0.727 |
AND_000270 | AND_002927 | W5JWD8 | W5JPT0 | HD domain-containing protein. | Thymidylate kinase. | 0.736 |
AND_000270 | AND_003305 | W5JWD8 | W5JNR5 | HD domain-containing protein. | Purine nucleoside phosphorylase. | 0.789 |
AND_000270 | AND_003308 | W5JWD8 | W5JKQ6 | HD domain-containing protein. | Purine nucleoside phosphorylase. | 0.789 |
AND_000270 | AND_003550 | W5JWD8 | W5JN05 | HD domain-containing protein. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | 0.894 |
AND_000270 | AND_006869 | W5JWD8 | W5JF89 | HD domain-containing protein. | Single-strand selective monofunctional uracil DNA glycosylase. | 0.884 |
AND_000270 | AND_007699 | W5JWD8 | W5JCW6 | HD domain-containing protein. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 0.735 |
AND_000270 | AND_008033 | W5JWD8 | W5JBZ5 | HD domain-containing protein. | Uncharacterized protein. | 0.755 |
AND_000270 | AND_008465 | W5JWD8 | W5JAR7 | HD domain-containing protein. | Deoxyuridine 5'-triphosphate nucleotidohydrolase. | 0.723 |
AND_000270 | AND_22863 | W5JWD8 | E3XFR6 | HD domain-containing protein. | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | 0.789 |
AND_001804 | AND_000270 | W5JTZ8 | W5JWD8 | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. | HD domain-containing protein. | 0.727 |
AND_001804 | AND_002927 | W5JTZ8 | W5JPT0 | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. | Thymidylate kinase. | 0.692 |
AND_001804 | AND_003305 | W5JTZ8 | W5JNR5 | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. | Purine nucleoside phosphorylase. | 0.917 |
AND_001804 | AND_003308 | W5JTZ8 | W5JKQ6 | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. | Purine nucleoside phosphorylase. | 0.917 |
AND_001804 | AND_006869 | W5JTZ8 | W5JF89 | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. | Single-strand selective monofunctional uracil DNA glycosylase. | 0.896 |
AND_001804 | AND_007699 | W5JTZ8 | W5JCW6 | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 0.992 |
AND_001804 | AND_008033 | W5JTZ8 | W5JBZ5 | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. | Uncharacterized protein. | 0.764 |
AND_001804 | AND_008465 | W5JTZ8 | W5JAR7 | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. | Deoxyuridine 5'-triphosphate nucleotidohydrolase. | 0.690 |
AND_001804 | AND_22863 | W5JTZ8 | E3XFR6 | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | 0.884 |
AND_002927 | AND_000270 | W5JPT0 | W5JWD8 | Thymidylate kinase. | HD domain-containing protein. | 0.736 |