K3WDB5_GLOUD protein (Globisporangium ultimum)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

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Score

K3WDB5_GLOUD

Uncharacterized protein; Belongs to the pirin family. (292 aa)

Predicted Functional Partners:

K3WCS2_GLOUD

0.591

K3WUK7_GLOUD

0.591

K3WUK8_GLOUD

0.591

K3X7P7_GLOUD

0.571

K3W5F1_GLOUD

0.547

K3W8Q5_GLOUD

0.547

K3WHX5_GLOUD

0.547

K3WJW0_GLOUD

0.547

K3X5K9_GLOUD

0.547

K3X5L0_GLOUD

0.547

Your Current Organism:

Globisporangium ultimum

NCBI taxonomy Id: 431595
Other names: G. ultimum DAOM BR144, Globisporangium ultimum DAOM BR144

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structured XML interaction data, according to the 'PSI-MI' data standard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
K3W5F1_GLOUD	K3W8Q5_GLOUD	K3W5F1	K3W8Q5	Cellulase domain-containing protein; Belongs to the glycosyl hydrolase 5 (cellulase A) family.	Alpha-amylase.	0.497
K3W5F1_GLOUD	K3WDB5_GLOUD	K3W5F1	K3WDB5	Cellulase domain-containing protein; Belongs to the glycosyl hydrolase 5 (cellulase A) family.	Uncharacterized protein; Belongs to the pirin family.	0.547
K3W5F1_GLOUD	K3WJW0_GLOUD	K3W5F1	K3WJW0	Cellulase domain-containing protein; Belongs to the glycosyl hydrolase 5 (cellulase A) family.	Alpha-amylase.	0.497
K3W8Q5_GLOUD	K3W5F1_GLOUD	K3W8Q5	K3W5F1	Alpha-amylase.	Cellulase domain-containing protein; Belongs to the glycosyl hydrolase 5 (cellulase A) family.	0.497
K3W8Q5_GLOUD	K3WDB5_GLOUD	K3W8Q5	K3WDB5	Alpha-amylase.	Uncharacterized protein; Belongs to the pirin family.	0.547
K3W8Q5_GLOUD	K3WHX5_GLOUD	K3W8Q5	K3WHX5	Alpha-amylase.	Fe2OG dioxygenase domain-containing protein.	0.497
K3W8Q5_GLOUD	K3X5K9_GLOUD	K3W8Q5	K3X5K9	Alpha-amylase.	Cellulase domain-containing protein; Belongs to the glycosyl hydrolase 5 (cellulase A) family.	0.497
K3W8Q5_GLOUD	K3X5L0_GLOUD	K3W8Q5	K3X5L0	Alpha-amylase.	Cellulase domain-containing protein; Belongs to the glycosyl hydrolase 5 (cellulase A) family.	0.497
K3WCS2_GLOUD	K3WDB5_GLOUD	K3WCS2	K3WDB5	Uncharacterized protein.	Uncharacterized protein; Belongs to the pirin family.	0.591
K3WDB5_GLOUD	K3W5F1_GLOUD	K3WDB5	K3W5F1	Uncharacterized protein; Belongs to the pirin family.	Cellulase domain-containing protein; Belongs to the glycosyl hydrolase 5 (cellulase A) family.	0.547
K3WDB5_GLOUD	K3W8Q5_GLOUD	K3WDB5	K3W8Q5	Uncharacterized protein; Belongs to the pirin family.	Alpha-amylase.	0.547
K3WDB5_GLOUD	K3WCS2_GLOUD	K3WDB5	K3WCS2	Uncharacterized protein; Belongs to the pirin family.	Uncharacterized protein.	0.591
K3WDB5_GLOUD	K3WHX5_GLOUD	K3WDB5	K3WHX5	Uncharacterized protein; Belongs to the pirin family.	Fe2OG dioxygenase domain-containing protein.	0.547
K3WDB5_GLOUD	K3WJW0_GLOUD	K3WDB5	K3WJW0	Uncharacterized protein; Belongs to the pirin family.	Alpha-amylase.	0.547
K3WDB5_GLOUD	K3WUK7_GLOUD	K3WDB5	K3WUK7	Uncharacterized protein; Belongs to the pirin family.	Uncharacterized protein.	0.591
K3WDB5_GLOUD	K3WUK8_GLOUD	K3WDB5	K3WUK8	Uncharacterized protein; Belongs to the pirin family.	Uncharacterized protein.	0.591
K3WDB5_GLOUD	K3X5K9_GLOUD	K3WDB5	K3X5K9	Uncharacterized protein; Belongs to the pirin family.	Cellulase domain-containing protein; Belongs to the glycosyl hydrolase 5 (cellulase A) family.	0.547
K3WDB5_GLOUD	K3X5L0_GLOUD	K3WDB5	K3X5L0	Uncharacterized protein; Belongs to the pirin family.	Cellulase domain-containing protein; Belongs to the glycosyl hydrolase 5 (cellulase A) family.	0.547
K3WDB5_GLOUD	K3X7P7_GLOUD	K3WDB5	K3X7P7	Uncharacterized protein; Belongs to the pirin family.	N-(5'-phosphoribosyl)anthranilate isomerase.	0.571
K3WHX5_GLOUD	K3W8Q5_GLOUD	K3WHX5	K3W8Q5	Fe2OG dioxygenase domain-containing protein.	Alpha-amylase.	0.497

page 1 of 2

Network Stats

number of nodes:

11

number of edges:

24

average node degree:

4.36

avg. local clustering coefficient:

0.903

expected number of edges:

10

PPI enrichment p-value:

0.000173

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006260

DNA replication

8 of 46

1.55

2.55

1.08e-08

GO:0006259

DNA metabolic process

9 of 117

1.19

1.57

1.10e-07

GO:0006261

DNA-templated DNA replication

3 of 16

1.58

1.09

0.0046

GO:0034654

Nucleobase-containing compound biosynthetic process

6 of 108

1.05

0.92

0.00065

GO:0006269

DNA replication, synthesis of RNA primer

2 of 5

1.91

0.87

0.0220

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003887

DNA-directed DNA polymerase activity

4 of 14

1.76

1.71

0.00019

GO:0016779

Nucleotidyltransferase activity

5 of 36

1.45

0.00019

GO:0140097

Catalytic activity, acting on DNA

6 of 66

1.26

1.25

0.00019

GO:0140640

Catalytic activity, acting on a nucleic acid

7 of 150

0.97

0.91

0.00019

GO:0003677

DNA binding

8 of 187

0.94

0.86

0.00019

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0030894

Replisome

3 of 6

2.0

1.57

0.00080

GO:0061695

Transferase complex, transferring phosphorus-containing groups

3 of 9

1.83

1.5

0.00080

GO:0009360

DNA polymerase III complex

2 of 3

2.13

1.33

0.0030

GO:0140535

Intracellular protein-containing complex

3 of 15

1.61

1.28

0.0015

GO:1990077

Primosome complex

2 of 4

2.0

1.26

0.0036

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:575

DNA replication, and Bacterial nucleoid

8 of 14

2.06

5.07

5.57e-13

CL:523

Mismatch repair, and DNA damage

10 of 40

1.7

3.97

6.50e-14

CL:591

Primosome, and Bacterial nucleoid

4 of 6

2.13

2.61

5.39e-06

CL:579

DNA polymerase III subunits gamma and tau domain III, and Helix-hairpin-helix motif

3 of 5

2.08

1.77

0.00034

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03030

DNA replication

7 of 31

1.66

2.86

7.89e-09

map03430

Mismatch repair

6 of 27

1.65

2.54

1.54e-07

map03440

Homologous recombination

6 of 36

1.53

2.18

4.78e-07

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0009360

DNA polymerase III complex

3 of 4

2.18

1.87

0.00024

GOCC:0061695

Transferase complex, transferring phosphorus-containing groups

5 of 31

1.51

1.62

8.25e-05

GOCC:1990077

Primosome complex

2 of 6

1.83

0.87

0.0204

GOCC:1902494

Catalytic complex

6 of 130

0.97

0.83

0.00077

GOCC:0032991

Protein-containing complex

7 of 315

0.65

0.46

0.0093

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0235

DNA replication

6 of 15

1.91

3.25

2.46e-08

KW-0238

DNA-binding

7 of 105

1.13

1.24

1.61e-05

KW-0639

Primosome

2 of 2

2.31

1.14

0.0076

KW-0239

DNA-directed DNA polymerase

2 of 5

1.91

0.94

0.0159

KW-0548

Nucleotidyltransferase

3 of 22

1.44

0.93

0.0084

(more ...)

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR027417

P-loop containing nucleoside triphosphate hydrolase

7 of 152

0.97

0.78

0.0019

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