STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAB42RAB42, member RAS oncogene family. (217 aa)    
Predicted Functional Partners:
ITSN2
Intersectin 2.
    
 0.950
ITSN1
Intersectin 1.
    
 0.904
C9orf72
C9orf72-SMCR8 complex subunit.
    
  0.825
CHM
Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.
    
 0.812
RABGGTA
Rab geranylgeranyltransferase subunit alpha.
    
 0.799
NOS1AP
Nitric oxide synthase 1 adaptor protein.
    
  0.785
SHANK3
SH3 and multiple ankyrin repeat domains 3.
   
 0.737
SHANK1
SH3 and multiple ankyrin repeat domains 1.
   
 0.737
COG6
Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function.
    
 0.734
SMCR8
SMCR8-C9orf72 complex subunit.
    
 0.729
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.