UBE2Z protein (Ictidomys tridecemlineatus) - STRING interaction network

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UBE2Z

Ubiquitin conjugating enzyme E2 Z. (288 aa)

Predicted Functional Partners:

ENSSTOP00000029566

0.972

UBE2V1

0.971

UBA6

0.960

TRIP12

0.910

UBOX5

0.856

UBA1

0.837

UBA3

0.831

UBA5

0.813

UBA7

0.807

ATG7

0.798

Your Current Organism:

Ictidomys tridecemlineatus

NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATG7	ENSSTOP00000029566	ENSSTOP00000026058	ENSSTOP00000029566	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	UBIQUITIN_CONJUGAT_2 domain-containing protein.	0.976
ATG7	TRIP12	ENSSTOP00000026058	ENSSTOP00000024104	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Thyroid hormone receptor interactor 12.	0.981
ATG7	UBA1	ENSSTOP00000026058	ENSSTOP00000009783	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Ubiquitin like modifier activating enzyme 1; Belongs to the ubiquitin-activating E1 family.	0.803
ATG7	UBA3	ENSSTOP00000026058	ENSSTOP00000002872	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Ubiquitin like modifier activating enzyme 3.	0.935
ATG7	UBA5	ENSSTOP00000026058	ENSSTOP00000010906	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Ubiquitin like modifier activating enzyme 5.	0.901
ATG7	UBA6	ENSSTOP00000026058	ENSSTOP00000015210	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Ubiquitin like modifier activating enzyme 6.	0.814
ATG7	UBA7	ENSSTOP00000026058	ENSSTOP00000012328	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Ubiquitin like modifier activating enzyme 7.	0.803
ATG7	UBE2V1	ENSSTOP00000026058	ENSSTOP00000012823	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Ubiquitin conjugating enzyme E2 V1.	0.978
ATG7	UBE2Z	ENSSTOP00000026058	ENSSTOP00000000713	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Ubiquitin conjugating enzyme E2 Z.	0.798
ATG7	UBOX5	ENSSTOP00000026058	ENSSTOP00000015886	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	U-box domain containing 5.	0.649
ENSSTOP00000029566	ATG7	ENSSTOP00000029566	ENSSTOP00000026058	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	0.976
ENSSTOP00000029566	TRIP12	ENSSTOP00000029566	ENSSTOP00000024104	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Thyroid hormone receptor interactor 12.	0.546
ENSSTOP00000029566	UBA1	ENSSTOP00000029566	ENSSTOP00000009783	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Ubiquitin like modifier activating enzyme 1; Belongs to the ubiquitin-activating E1 family.	0.983
ENSSTOP00000029566	UBA3	ENSSTOP00000029566	ENSSTOP00000002872	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Ubiquitin like modifier activating enzyme 3.	0.981
ENSSTOP00000029566	UBA5	ENSSTOP00000029566	ENSSTOP00000010906	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Ubiquitin like modifier activating enzyme 5.	0.976
ENSSTOP00000029566	UBA6	ENSSTOP00000029566	ENSSTOP00000015210	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Ubiquitin like modifier activating enzyme 6.	0.983
ENSSTOP00000029566	UBA7	ENSSTOP00000029566	ENSSTOP00000012328	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Ubiquitin like modifier activating enzyme 7.	0.983
ENSSTOP00000029566	UBE2V1	ENSSTOP00000029566	ENSSTOP00000012823	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Ubiquitin conjugating enzyme E2 V1.	0.984
ENSSTOP00000029566	UBE2Z	ENSSTOP00000029566	ENSSTOP00000000713	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Ubiquitin conjugating enzyme E2 Z.	0.972
TRIP12	ATG7	ENSSTOP00000024104	ENSSTOP00000026058	Thyroid hormone receptor interactor 12.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	0.981