OS9 protein (Ictidomys tridecemlineatus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

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[Homology]

Score

OS9

OS9 endoplasmic reticulum lectin. (666 aa)

Predicted Functional Partners:

SEL1L

0.991

DERL1

0.985

DERL2

0.983

SYVN1

0.976

DERL3

0.970

AMFR

0.966

VCP

0.953

SEL1L2

0.950

HSP90B1

0.944

SEL1L3

0.936

Your Current Organism:

Ictidomys tridecemlineatus

NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AMFR	DERL1	ENSSTOP00000006944	ENSSTOP00000023908	Autocrine motility factor receptor.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.992
AMFR	DERL2	ENSSTOP00000006944	ENSSTOP00000016872	Autocrine motility factor receptor.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.965
AMFR	DERL3	ENSSTOP00000006944	ENSSTOP00000011129	Autocrine motility factor receptor.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.965
AMFR	HSP90B1	ENSSTOP00000006944	ENSSTOP00000004763	Autocrine motility factor receptor.	Heat shock protein 90 beta family member 1.	0.498
AMFR	OS9	ENSSTOP00000006944	ENSSTOP00000000982	Autocrine motility factor receptor.	OS9 endoplasmic reticulum lectin.	0.966
AMFR	SEL1L	ENSSTOP00000006944	ENSSTOP00000024203	Autocrine motility factor receptor.	SEL1L adaptor subunit of ERAD E3 ubiquitin ligase.	0.967
AMFR	SEL1L2	ENSSTOP00000006944	ENSSTOP00000008868	Autocrine motility factor receptor.	SEL1L2 adaptor subunit of ERAD E3 ligase.	0.938
AMFR	SEL1L3	ENSSTOP00000006944	ENSSTOP00000009355	Autocrine motility factor receptor.	SEL1L family member 3.	0.931
AMFR	SYVN1	ENSSTOP00000006944	ENSSTOP00000028521	Autocrine motility factor receptor.	Synoviolin 1.	0.603
AMFR	VCP	ENSSTOP00000006944	ENSSTOP00000013606	Autocrine motility factor receptor.	Valosin containing protein; Belongs to the AAA ATPase family.	0.991
DERL1	AMFR	ENSSTOP00000023908	ENSSTOP00000006944	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Autocrine motility factor receptor.	0.992
DERL1	DERL2	ENSSTOP00000023908	ENSSTOP00000016872	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.978
DERL1	DERL3	ENSSTOP00000023908	ENSSTOP00000011129	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.978
DERL1	HSP90B1	ENSSTOP00000023908	ENSSTOP00000004763	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Heat shock protein 90 beta family member 1.	0.585
DERL1	OS9	ENSSTOP00000023908	ENSSTOP00000000982	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	OS9 endoplasmic reticulum lectin.	0.985
DERL1	SEL1L	ENSSTOP00000023908	ENSSTOP00000024203	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	SEL1L adaptor subunit of ERAD E3 ubiquitin ligase.	0.992
DERL1	SEL1L2	ENSSTOP00000023908	ENSSTOP00000008868	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	SEL1L2 adaptor subunit of ERAD E3 ligase.	0.983
DERL1	SEL1L3	ENSSTOP00000023908	ENSSTOP00000009355	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	SEL1L family member 3.	0.980
DERL1	SYVN1	ENSSTOP00000023908	ENSSTOP00000028521	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Synoviolin 1.	0.993
DERL1	VCP	ENSSTOP00000023908	ENSSTOP00000013606	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Valosin containing protein; Belongs to the AAA ATPase family.	0.993