RET protein (Ictidomys tridecemlineatus) - STRING interaction network

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RET

Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1112 aa)

Predicted Functional Partners:

GFRA2

0.997

NRTN

0.996

GRB2

0.996

EGFR

0.993

STAT3

0.993

GFRA3

0.992

PLCG1

0.990

SHC1

0.982

Fgf2

0.979

ERBB2

0.978

Your Current Organism:

Ictidomys tridecemlineatus

NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EGFR	ERBB2	ENSSTOP00000006038	ENSSTOP00000003374	Receptor protein-tyrosine kinase.	Receptor protein-tyrosine kinase.	0.999
EGFR	Fgf2	ENSSTOP00000006038	ENSSTOP00000015653	Receptor protein-tyrosine kinase.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.956
EGFR	GRB2	ENSSTOP00000006038	ENSSTOP00000011345	Receptor protein-tyrosine kinase.	Growth factor receptor bound protein 2.	0.999
EGFR	NRTN	ENSSTOP00000006038	ENSSTOP00000008556	Receptor protein-tyrosine kinase.	Neurturin.	0.917
EGFR	PLCG1	ENSSTOP00000006038	ENSSTOP00000010469	Receptor protein-tyrosine kinase.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.999
EGFR	RET	ENSSTOP00000006038	ENSSTOP00000001331	Receptor protein-tyrosine kinase.	Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands.	0.993
EGFR	SHC1	ENSSTOP00000006038	ENSSTOP00000000045	Receptor protein-tyrosine kinase.	SHC adaptor protein 1.	0.999
EGFR	STAT3	ENSSTOP00000006038	ENSSTOP00000006050	Receptor protein-tyrosine kinase.	Signal transducer and activator of transcription.	0.999
ERBB2	EGFR	ENSSTOP00000003374	ENSSTOP00000006038	Receptor protein-tyrosine kinase.	Receptor protein-tyrosine kinase.	0.999
ERBB2	Fgf2	ENSSTOP00000003374	ENSSTOP00000015653	Receptor protein-tyrosine kinase.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.938
ERBB2	GRB2	ENSSTOP00000003374	ENSSTOP00000011345	Receptor protein-tyrosine kinase.	Growth factor receptor bound protein 2.	0.999
ERBB2	NRTN	ENSSTOP00000003374	ENSSTOP00000008556	Receptor protein-tyrosine kinase.	Neurturin.	0.917
ERBB2	PLCG1	ENSSTOP00000003374	ENSSTOP00000010469	Receptor protein-tyrosine kinase.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.995
ERBB2	RET	ENSSTOP00000003374	ENSSTOP00000001331	Receptor protein-tyrosine kinase.	Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands.	0.978
ERBB2	SHC1	ENSSTOP00000003374	ENSSTOP00000000045	Receptor protein-tyrosine kinase.	SHC adaptor protein 1.	0.999
ERBB2	STAT3	ENSSTOP00000003374	ENSSTOP00000006050	Receptor protein-tyrosine kinase.	Signal transducer and activator of transcription.	0.995
Fgf2	EGFR	ENSSTOP00000015653	ENSSTOP00000006038	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Receptor protein-tyrosine kinase.	0.956
Fgf2	ERBB2	ENSSTOP00000015653	ENSSTOP00000003374	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Receptor protein-tyrosine kinase.	0.938
Fgf2	GRB2	ENSSTOP00000015653	ENSSTOP00000011345	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Growth factor receptor bound protein 2.	0.600
Fgf2	PLCG1	ENSSTOP00000015653	ENSSTOP00000010469	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.595

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