DMPK protein (Ictidomys tridecemlineatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

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Coexpression

Experiments

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[Homology]

Score

DMPK

DM1 protein kinase. (629 aa)

Predicted Functional Partners:

WDR90

0.754

RHOQ

0.723

MYL7

0.713

PTEN

0.699

ITSN2

0.696

MYLPF

0.692

LIMK1

0.692

LIMK2

0.692

RHOJ

0.684

RHOBTB2

0.682

Your Current Organism:

Ictidomys tridecemlineatus

NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DMPK	ITSN2	ENSSTOP00000001355	ENSSTOP00000002868	DM1 protein kinase.	Intersectin 2.	0.696
DMPK	LIMK1	ENSSTOP00000001355	ENSSTOP00000011471	DM1 protein kinase.	LIM domain kinase 1.	0.692
DMPK	LIMK2	ENSSTOP00000001355	ENSSTOP00000020688	DM1 protein kinase.	LIM domain kinase 2.	0.692
DMPK	MYL7	ENSSTOP00000001355	ENSSTOP00000002437	DM1 protein kinase.	Myosin light chain 7.	0.713
DMPK	MYLPF	ENSSTOP00000001355	ENSSTOP00000002474	DM1 protein kinase.	Myosin light chain, phosphorylatable, fast skeletal muscle.	0.692
DMPK	PTEN	ENSSTOP00000001355	ENSSTOP00000015636	DM1 protein kinase.	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	0.699
DMPK	RHOBTB2	ENSSTOP00000001355	ENSSTOP00000015053	DM1 protein kinase.	Rho related BTB domain containing 2.	0.682
DMPK	RHOJ	ENSSTOP00000001355	ENSSTOP00000002149	DM1 protein kinase.	Ras homolog family member J.	0.684
DMPK	RHOQ	ENSSTOP00000001355	ENSSTOP00000001225	DM1 protein kinase.	Ras homolog family member Q.	0.723
DMPK	WDR90	ENSSTOP00000001355	ENSSTOP00000029448	DM1 protein kinase.	WD repeat domain 90.	0.754
ITSN2	DMPK	ENSSTOP00000002868	ENSSTOP00000001355	Intersectin 2.	DM1 protein kinase.	0.696
ITSN2	LIMK1	ENSSTOP00000002868	ENSSTOP00000011471	Intersectin 2.	LIM domain kinase 1.	0.658
ITSN2	LIMK2	ENSSTOP00000002868	ENSSTOP00000020688	Intersectin 2.	LIM domain kinase 2.	0.658
ITSN2	RHOBTB2	ENSSTOP00000002868	ENSSTOP00000015053	Intersectin 2.	Rho related BTB domain containing 2.	0.998
ITSN2	RHOJ	ENSSTOP00000002868	ENSSTOP00000002149	Intersectin 2.	Ras homolog family member J.	0.998
ITSN2	RHOQ	ENSSTOP00000002868	ENSSTOP00000001225	Intersectin 2.	Ras homolog family member Q.	0.998
LIMK1	DMPK	ENSSTOP00000011471	ENSSTOP00000001355	LIM domain kinase 1.	DM1 protein kinase.	0.692
LIMK1	ITSN2	ENSSTOP00000011471	ENSSTOP00000002868	LIM domain kinase 1.	Intersectin 2.	0.658
LIMK1	LIMK2	ENSSTOP00000011471	ENSSTOP00000020688	LIM domain kinase 1.	LIM domain kinase 2.	0.899
LIMK1	RHOBTB2	ENSSTOP00000011471	ENSSTOP00000015053	LIM domain kinase 1.	Rho related BTB domain containing 2.	0.461