EIF2S1 protein (Ictidomys tridecemlineatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Ictidomys tridecemlineatus

NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EIF2AK2	EIF2AK3	ENSSTOP00000012442	ENSSTOP00000008691	Eukaryotic translation initiation factor 2 alpha kinase 2.	Eukaryotic translation initiation factor 2 alpha kinase 3.	0.876
EIF2AK2	EIF2AK4	ENSSTOP00000012442	ENSSTOP00000013982	Eukaryotic translation initiation factor 2 alpha kinase 2.	Eukaryotic translation initiation factor 2 alpha kinase 4.	0.917
EIF2AK2	EIF2S1	ENSSTOP00000012442	ENSSTOP00000001402	Eukaryotic translation initiation factor 2 alpha kinase 2.	Eukaryotic translation initiation factor 2 subunit alpha.	0.999
EIF2AK2	EIF2S2	ENSSTOP00000012442	ENSSTOP00000007912	Eukaryotic translation initiation factor 2 alpha kinase 2.	Eukaryotic translation initiation factor 2 subunit beta.	0.683
EIF2AK2	ENSSTOP00000031876	ENSSTOP00000012442	ENSSTOP00000031876	Eukaryotic translation initiation factor 2 alpha kinase 2.	Tr-type G domain-containing protein.	0.577
EIF2AK2	Eif2s3	ENSSTOP00000012442	ENSSTOP00000006387	Eukaryotic translation initiation factor 2 alpha kinase 2.	Tr-type G domain-containing protein.	0.577
EIF2AK3	EIF2AK2	ENSSTOP00000008691	ENSSTOP00000012442	Eukaryotic translation initiation factor 2 alpha kinase 3.	Eukaryotic translation initiation factor 2 alpha kinase 2.	0.876
EIF2AK3	EIF2AK4	ENSSTOP00000008691	ENSSTOP00000013982	Eukaryotic translation initiation factor 2 alpha kinase 3.	Eukaryotic translation initiation factor 2 alpha kinase 4.	0.947
EIF2AK3	EIF2S1	ENSSTOP00000008691	ENSSTOP00000001402	Eukaryotic translation initiation factor 2 alpha kinase 3.	Eukaryotic translation initiation factor 2 subunit alpha.	0.997
EIF2AK3	EIF2S2	ENSSTOP00000008691	ENSSTOP00000007912	Eukaryotic translation initiation factor 2 alpha kinase 3.	Eukaryotic translation initiation factor 2 subunit beta.	0.783
EIF2AK3	ENSSTOP00000031876	ENSSTOP00000008691	ENSSTOP00000031876	Eukaryotic translation initiation factor 2 alpha kinase 3.	Tr-type G domain-containing protein.	0.680
EIF2AK3	Eif2s3	ENSSTOP00000008691	ENSSTOP00000006387	Eukaryotic translation initiation factor 2 alpha kinase 3.	Tr-type G domain-containing protein.	0.680
EIF2AK4	EIF2AK2	ENSSTOP00000013982	ENSSTOP00000012442	Eukaryotic translation initiation factor 2 alpha kinase 4.	Eukaryotic translation initiation factor 2 alpha kinase 2.	0.917
EIF2AK4	EIF2AK3	ENSSTOP00000013982	ENSSTOP00000008691	Eukaryotic translation initiation factor 2 alpha kinase 4.	Eukaryotic translation initiation factor 2 alpha kinase 3.	0.947
EIF2AK4	EIF2S1	ENSSTOP00000013982	ENSSTOP00000001402	Eukaryotic translation initiation factor 2 alpha kinase 4.	Eukaryotic translation initiation factor 2 subunit alpha.	0.998
EIF2AK4	EIF2S2	ENSSTOP00000013982	ENSSTOP00000007912	Eukaryotic translation initiation factor 2 alpha kinase 4.	Eukaryotic translation initiation factor 2 subunit beta.	0.843
EIF2AK4	EIF3B	ENSSTOP00000013982	ENSSTOP00000018430	Eukaryotic translation initiation factor 2 alpha kinase 4.	Eukaryotic translation initiation factor 3 subunit B; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form [...]	0.523
EIF2AK4	ENSSTOP00000031876	ENSSTOP00000013982	ENSSTOP00000031876	Eukaryotic translation initiation factor 2 alpha kinase 4.	Tr-type G domain-containing protein.	0.865
EIF2AK4	Eif2s3	ENSSTOP00000013982	ENSSTOP00000006387	Eukaryotic translation initiation factor 2 alpha kinase 4.	Tr-type G domain-containing protein.	0.865
EIF2AK4	Rps3	ENSSTOP00000013982	ENSSTOP00000024446	Eukaryotic translation initiation factor 2 alpha kinase 4.	KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family.	0.465