node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ALDH18A1 | OXGR1 | ENSSTOP00000007111 | ENSSTOP00000001429 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Oxoglutarate receptor 1. | 0.618 |
CNR1 | CNR2 | ENSSTOP00000022582 | ENSSTOP00000010713 | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] | Cannabinoid receptor 2; Belongs to the G-protein coupled receptor 1 family. | 0.878 |
CNR1 | GPR50 | ENSSTOP00000022582 | ENSSTOP00000000086 | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] | G protein-coupled receptor 50; Belongs to the G-protein coupled receptor 1 family. | 0.466 |
CNR1 | Hcar2 | ENSSTOP00000022582 | ENSSTOP00000023067 | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. | 0.438 |
CNR1 | OXGR1 | ENSSTOP00000022582 | ENSSTOP00000001429 | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] | Oxoglutarate receptor 1. | 0.550 |
CNR2 | CNR1 | ENSSTOP00000010713 | ENSSTOP00000022582 | Cannabinoid receptor 2; Belongs to the G-protein coupled receptor 1 family. | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] | 0.878 |
CNR2 | GPR50 | ENSSTOP00000010713 | ENSSTOP00000000086 | Cannabinoid receptor 2; Belongs to the G-protein coupled receptor 1 family. | G protein-coupled receptor 50; Belongs to the G-protein coupled receptor 1 family. | 0.466 |
CNR2 | Hcar2 | ENSSTOP00000010713 | ENSSTOP00000023067 | Cannabinoid receptor 2; Belongs to the G-protein coupled receptor 1 family. | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. | 0.438 |
CNR2 | OXGR1 | ENSSTOP00000010713 | ENSSTOP00000001429 | Cannabinoid receptor 2; Belongs to the G-protein coupled receptor 1 family. | Oxoglutarate receptor 1. | 0.550 |
GPR50 | CNR1 | ENSSTOP00000000086 | ENSSTOP00000022582 | G protein-coupled receptor 50; Belongs to the G-protein coupled receptor 1 family. | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] | 0.466 |
GPR50 | CNR2 | ENSSTOP00000000086 | ENSSTOP00000010713 | G protein-coupled receptor 50; Belongs to the G-protein coupled receptor 1 family. | Cannabinoid receptor 2; Belongs to the G-protein coupled receptor 1 family. | 0.466 |
GPR50 | Hcar2 | ENSSTOP00000000086 | ENSSTOP00000023067 | G protein-coupled receptor 50; Belongs to the G-protein coupled receptor 1 family. | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. | 0.405 |
GPR50 | OXGR1 | ENSSTOP00000000086 | ENSSTOP00000001429 | G protein-coupled receptor 50; Belongs to the G-protein coupled receptor 1 family. | Oxoglutarate receptor 1. | 0.535 |
Hcar2 | CNR1 | ENSSTOP00000023067 | ENSSTOP00000022582 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] | 0.438 |
Hcar2 | CNR2 | ENSSTOP00000023067 | ENSSTOP00000010713 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. | Cannabinoid receptor 2; Belongs to the G-protein coupled receptor 1 family. | 0.438 |
Hcar2 | GPR50 | ENSSTOP00000023067 | ENSSTOP00000000086 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. | G protein-coupled receptor 50; Belongs to the G-protein coupled receptor 1 family. | 0.405 |
Hcar2 | OXGR1 | ENSSTOP00000023067 | ENSSTOP00000001429 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. | Oxoglutarate receptor 1. | 0.474 |
Hcar2 | SUCNR1 | ENSSTOP00000023067 | ENSSTOP00000014894 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. | Succinate receptor 1; Belongs to the G-protein coupled receptor 1 family. | 0.516 |
OXGR1 | ALDH18A1 | ENSSTOP00000001429 | ENSSTOP00000007111 | Oxoglutarate receptor 1. | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | 0.618 |
OXGR1 | CNR1 | ENSSTOP00000001429 | ENSSTOP00000022582 | Oxoglutarate receptor 1. | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] | 0.550 |