PDE10A protein (Ictidomys tridecemlineatus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

PDE10A

Phosphodiesterase. (794 aa)

Predicted Functional Partners:

GUCY2C

0.940

I3MMP4_ICTTR

0.925

PDE6G

0.916

ADCY5

0.901

ADCY6

0.901

PRKACB

0.901

AMPD3

0.900

PRKACA

0.899

NPR2

0.883

NPR1

0.883

Your Current Organism:

Ictidomys tridecemlineatus

NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCY5	ADCY6	ENSSTOP00000000037	ENSSTOP00000003745	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.873
ADCY5	I3MMP4_ICTTR	ENSSTOP00000000037	ENSSTOP00000012821	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	NUC domain-containing protein.	0.876
ADCY5	PDE10A	ENSSTOP00000000037	ENSSTOP00000001742	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Phosphodiesterase.	0.901
ADCY5	PDE6G	ENSSTOP00000000037	ENSSTOP00000000072	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Phosphodiesterase 6G.	0.856
ADCY5	PRKACA	ENSSTOP00000000037	ENSSTOP00000002080	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily.	0.928
ADCY5	PRKACB	ENSSTOP00000000037	ENSSTOP00000028928	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.	0.928
ADCY6	ADCY5	ENSSTOP00000003745	ENSSTOP00000000037	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.873
ADCY6	I3MMP4_ICTTR	ENSSTOP00000003745	ENSSTOP00000012821	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	NUC domain-containing protein.	0.876
ADCY6	PDE10A	ENSSTOP00000003745	ENSSTOP00000001742	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Phosphodiesterase.	0.901
ADCY6	PDE6G	ENSSTOP00000003745	ENSSTOP00000000072	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Phosphodiesterase 6G.	0.856
ADCY6	PRKACA	ENSSTOP00000003745	ENSSTOP00000002080	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily.	0.926
ADCY6	PRKACB	ENSSTOP00000003745	ENSSTOP00000028928	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.	0.929
AMPD3	I3MMP4_ICTTR	ENSSTOP00000032278	ENSSTOP00000012821	AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.	NUC domain-containing protein.	0.872
AMPD3	PDE10A	ENSSTOP00000032278	ENSSTOP00000001742	AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.	Phosphodiesterase.	0.900
GUCY2C	I3MMP4_ICTTR	ENSSTOP00000000490	ENSSTOP00000012821	Guanylate cyclase.	NUC domain-containing protein.	0.927
GUCY2C	NPR1	ENSSTOP00000000490	ENSSTOP00000019888	Guanylate cyclase.	Guanylate cyclase.	0.554
GUCY2C	NPR2	ENSSTOP00000000490	ENSSTOP00000006186	Guanylate cyclase.	Guanylate cyclase.	0.544
GUCY2C	PDE10A	ENSSTOP00000000490	ENSSTOP00000001742	Guanylate cyclase.	Phosphodiesterase.	0.940
GUCY2C	PDE6G	ENSSTOP00000000490	ENSSTOP00000000072	Guanylate cyclase.	Phosphodiesterase 6G.	0.875
GUCY2C	PRKACA	ENSSTOP00000000490	ENSSTOP00000002080	Guanylate cyclase.	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily.	0.416