node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AGO2 | DICER1 | ENSSTOP00000007282 | ENSSTOP00000023439 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Dicer 1, ribonuclease III; Belongs to the helicase family. Dicer subfamily. | 0.994 |
AGO2 | MTDH | ENSSTOP00000007282 | ENSSTOP00000004560 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Metadherin. | 0.559 |
AGO2 | SERBP1 | ENSSTOP00000007282 | ENSSTOP00000029543 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | SERPINE1 mRNA binding protein 1. | 0.451 |
AGO2 | SND1 | ENSSTOP00000007282 | ENSSTOP00000001921 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Staphylococcal nuclease domain-containing protein; Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs. | 0.746 |
DICER1 | AGO2 | ENSSTOP00000023439 | ENSSTOP00000007282 | Dicer 1, ribonuclease III; Belongs to the helicase family. Dicer subfamily. | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | 0.994 |
DICER1 | I3M8U5_ICTTR | ENSSTOP00000023439 | ENSSTOP00000006211 | Dicer 1, ribonuclease III; Belongs to the helicase family. Dicer subfamily. | Piwi domain-containing protein. | 0.678 |
DICER1 | PIWIL1 | ENSSTOP00000023439 | ENSSTOP00000004637 | Dicer 1, ribonuclease III; Belongs to the helicase family. Dicer subfamily. | Piwi like RNA-mediated gene silencing 1; Belongs to the argonaute family. | 0.703 |
DICER1 | PIWIL2 | ENSSTOP00000023439 | ENSSTOP00000014787 | Dicer 1, ribonuclease III; Belongs to the helicase family. Dicer subfamily. | Piwi like RNA-mediated gene silencing 2; Belongs to the argonaute family. | 0.596 |
DICER1 | SND1 | ENSSTOP00000023439 | ENSSTOP00000001921 | Dicer 1, ribonuclease III; Belongs to the helicase family. Dicer subfamily. | Staphylococcal nuclease domain-containing protein; Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs. | 0.741 |
GANAB | SND1 | ENSSTOP00000002643 | ENSSTOP00000001921 | Glucosidase II alpha subunit; Belongs to the glycosyl hydrolase 31 family. | Staphylococcal nuclease domain-containing protein; Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs. | 0.794 |
I3M8U5_ICTTR | DICER1 | ENSSTOP00000006211 | ENSSTOP00000023439 | Piwi domain-containing protein. | Dicer 1, ribonuclease III; Belongs to the helicase family. Dicer subfamily. | 0.678 |
I3M8U5_ICTTR | SND1 | ENSSTOP00000006211 | ENSSTOP00000001921 | Piwi domain-containing protein. | Staphylococcal nuclease domain-containing protein; Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs. | 0.766 |
MTDH | AGO2 | ENSSTOP00000004560 | ENSSTOP00000007282 | Metadherin. | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | 0.559 |
MTDH | SND1 | ENSSTOP00000004560 | ENSSTOP00000001921 | Metadherin. | Staphylococcal nuclease domain-containing protein; Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs. | 0.972 |
PIWIL1 | DICER1 | ENSSTOP00000004637 | ENSSTOP00000023439 | Piwi like RNA-mediated gene silencing 1; Belongs to the argonaute family. | Dicer 1, ribonuclease III; Belongs to the helicase family. Dicer subfamily. | 0.703 |
PIWIL1 | SND1 | ENSSTOP00000004637 | ENSSTOP00000001921 | Piwi like RNA-mediated gene silencing 1; Belongs to the argonaute family. | Staphylococcal nuclease domain-containing protein; Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs. | 0.794 |
PIWIL2 | DICER1 | ENSSTOP00000014787 | ENSSTOP00000023439 | Piwi like RNA-mediated gene silencing 2; Belongs to the argonaute family. | Dicer 1, ribonuclease III; Belongs to the helicase family. Dicer subfamily. | 0.596 |
PIWIL2 | SND1 | ENSSTOP00000014787 | ENSSTOP00000001921 | Piwi like RNA-mediated gene silencing 2; Belongs to the argonaute family. | Staphylococcal nuclease domain-containing protein; Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs. | 0.756 |
SEC61A1 | SND1 | ENSSTOP00000027365 | ENSSTOP00000001921 | SEC61 translocon alpha 1 subunit. | Staphylococcal nuclease domain-containing protein; Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs. | 0.744 |
SEC61A2 | SND1 | ENSSTOP00000031900 | ENSSTOP00000001921 | SEC61 translocon alpha 2 subunit. | Staphylococcal nuclease domain-containing protein; Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs. | 0.744 |