IGFBP7 protein (Ictidomys tridecemlineatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

IGFBP7

Insulin like growth factor binding protein 7. (279 aa)

Predicted Functional Partners:

IGF1

0.662

Ins

0.609

IGF2

0.537

FREM1

0.485

FREM3

0.485

FAM20A

0.408

P4HB

0.408

Your Current Organism:

Ictidomys tridecemlineatus

NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FAM20A	IGFBP7	ENSSTOP00000016726	ENSSTOP00000003475	FAM20A golgi associated secretory pathway pseudokinase.	Insulin like growth factor binding protein 7.	0.408
FREM1	FREM3	ENSSTOP00000002927	ENSSTOP00000015498	FRAS1 related extracellular matrix 1.	FRAS1 related extracellular matrix 3.	0.883
FREM1	IGFBP7	ENSSTOP00000002927	ENSSTOP00000003475	FRAS1 related extracellular matrix 1.	Insulin like growth factor binding protein 7.	0.485
FREM3	FREM1	ENSSTOP00000015498	ENSSTOP00000002927	FRAS1 related extracellular matrix 3.	FRAS1 related extracellular matrix 1.	0.883
FREM3	IGFBP7	ENSSTOP00000015498	ENSSTOP00000003475	FRAS1 related extracellular matrix 3.	Insulin like growth factor binding protein 7.	0.485
IGF1	IGF2	ENSSTOP00000029785	ENSSTOP00000018700	Insulin like growth factor 1.	Insulin like growth factor 2.	0.934
IGF1	IGFBP7	ENSSTOP00000029785	ENSSTOP00000003475	Insulin like growth factor 1.	Insulin like growth factor binding protein 7.	0.662
IGF1	Ins	ENSSTOP00000029785	ENSSTOP00000017025	Insulin like growth factor 1.	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.956
IGF2	IGF1	ENSSTOP00000018700	ENSSTOP00000029785	Insulin like growth factor 2.	Insulin like growth factor 1.	0.934
IGF2	IGFBP7	ENSSTOP00000018700	ENSSTOP00000003475	Insulin like growth factor 2.	Insulin like growth factor binding protein 7.	0.537
IGF2	Ins	ENSSTOP00000018700	ENSSTOP00000017025	Insulin like growth factor 2.	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.888
IGFBP7	FAM20A	ENSSTOP00000003475	ENSSTOP00000016726	Insulin like growth factor binding protein 7.	FAM20A golgi associated secretory pathway pseudokinase.	0.408
IGFBP7	FREM1	ENSSTOP00000003475	ENSSTOP00000002927	Insulin like growth factor binding protein 7.	FRAS1 related extracellular matrix 1.	0.485
IGFBP7	FREM3	ENSSTOP00000003475	ENSSTOP00000015498	Insulin like growth factor binding protein 7.	FRAS1 related extracellular matrix 3.	0.485
IGFBP7	IGF1	ENSSTOP00000003475	ENSSTOP00000029785	Insulin like growth factor binding protein 7.	Insulin like growth factor 1.	0.662
IGFBP7	IGF2	ENSSTOP00000003475	ENSSTOP00000018700	Insulin like growth factor binding protein 7.	Insulin like growth factor 2.	0.537
IGFBP7	Ins	ENSSTOP00000003475	ENSSTOP00000017025	Insulin like growth factor binding protein 7.	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.609
IGFBP7	P4HB	ENSSTOP00000003475	ENSSTOP00000021866	Insulin like growth factor binding protein 7.	Protein disulfide-isomerase.	0.408
Ins	IGF1	ENSSTOP00000017025	ENSSTOP00000029785	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Insulin like growth factor 1.	0.956
Ins	IGF2	ENSSTOP00000017025	ENSSTOP00000018700	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Insulin like growth factor 2.	0.888